SI
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Data sourced from SEC EDGAR 13F filings

PricingTermsPrivacy© 2026 Super Investor · Not financial advice

Joseph Edelman – Perceptive Advisors LLC

Period:
Q1 2026
Portfolio date:
Mar 31, 2026
No. of stocks:
94
Portfolio value:
$5,117,576,000
Filed:
May 29, 2026
Style:
Biotech Specialist
HistStockActivityShare change% change to portfolio
Q1 2026filed May 29, 2620 new17 added21 reduced42 exited
≡XBIPUT – SPDR SERIES TRUSTSell−1,100,000−2.39
≡EXACT SCIENCES CORPSell−1,200,487−2.17
≡ARCELLX INCSell−1,466,071−1.70
≡BSX – BOSTON SCIENTIFIC CORPSell−979,000−1.66
≡AMICUS THERAPEUTICS INCSell−6,370,851−1.62
≡ASTRIA THERAPEUTICS INCSell−6,485,420−1.51
≡VRDN – VIRIDIAN THERAPEUTICS INCReduce 62.00%−1,871,874−1.24
≡RYTM – RHYTHM PHARMACEUTICALS INCReduce 7.00%−172,596−0.82
≡DHR – DANAHER CORPORATIONSell−200,000−0.82
≡BLTE – BELITE BIO INCReduce 63.00%−262,260−0.71
≡NBIX – NEUROCRINE BIOSCIENCES INCReduce 80.00%−266,000−0.67
≡CIDARA THERAPEUTICS INCSell−165,131−0.65
≡IRON – DISC MEDICINE INCSell−450,743−0.64
≡PEN – PENUMBRA INCSell−110,529−0.61
≡APGE – APOGEE THERAPEUTICS INCReduce 34.00%−790,267−0.60
≡CAI – CARIS LIFE SCIENCES INCSell−1,136,206−0.55
≡RAPT THERAPEUTICS INCSell−825,890−0.50
≡PALVELLA THERAPEUTICS INC NESell−266,287−0.50
≡OMDA – OMADA HEALTH INCReduce 67.00%−1,610,000−0.48
≡PTGX – PROTAGONIST THERAPEUTICS INCReduce 9.00%−119,5460.43
≡KOD – KODIAK SCIENCES INCSell−848,900−0.42
≡BIIB – BIOGEN INCSell−124,000−0.39
≡ALDX – ALDEYRA THERAPEUTICS INCSell−4,185,632−0.39
≡ABVX – ABIVAX SAReduce 28.00%−129,459−0.39
≡MIRM – MIRUM PHARMACEUTICALS INCSell−259,545−0.37
≡GRAL – GRAIL INCSell−237,342−0.36
≡SION – SIONNA THERAPEUTICS INCReduce 44.00%−520,659−0.35
≡CVS – CVS HEALTH CORPSell−220,000−0.31
≡GKOS – GLAUKOS CORPSell−140,000−0.28
≡RGEN – REPLIGEN CORPReduce 11.00%−35,000−0.28
≡DXCM – DEXCOM INCSell−225,758−0.27
≡SAVARA INCSell−2,400,000−0.26
≡SEPN – SEPTERNA INCSell−433,160−0.22
≡ADMA – ADMA BIOLOGICS INCReduce 47.00%−416,235−0.20
≡PALISADE BIO INCReduce 26.00%−3,121,851−0.20
≡GOSS – GOSSAMER BIO INCSell−3,139,669−0.17
≡MAPLIGHT THERAPEUTICS INCSell−550,000−0.17
≡XENE – XENON PHARMACEUTICALS INCSell−200,791−0.16
≡KESTRA MED TECHNOLOGIES LTDSell−285,000−0.13
≡IMVT – IMMUNOVANT INCReduce 20.00%−397,507−0.13
≡CAPRICOR THERAPEUTICS INCSell−242,100−0.12
≡IKT – INHIBIKASE THERAPEUTICS INCReduce 57.00%−3,106,568−0.12
≡BHVNCALL – BIOHAVEN LTDSell−500,000−0.10
≡KYMR – KYMERA THERAPEUTICS INCSell−69,935−0.10
≡PEPG – PEPGEN INCSell−829,870−0.10
≡TECTONIC THERAPEUTIC INCSell−250,000−0.09
≡DRUG – BRIGHT MINDS BIOSCIENCES INCReduce 16.00%−71,746−0.09
≡AQST – AQUESTIVE THERAPEUTICS INCSell−747,193−0.09
≡KRYS – KRYSTAL BIOTECH INCSell−17,500−0.08
≡OLMA – OLEMA PHARMACEUTICALS INCSell−165,713−0.07
≡SDGR – SCHRODINGER INCSell−202,400−0.06
≡IMMIX BIOPHARMA INCSell−338,941−0.03
≡LXEO – LEXEO THERAPEUTICS INCSell−139,835−0.02
≡CTNM – CONTINEUM THERAPEUTICS INCReduce 14.00%−209,0000.02
≡CBIO – CRESCENT BIOPHARMA INC.Reduce 54.00%−246,744−0.02
≡LENZ THERAPEUTICS INCSell−50,000−0.01
≡BIODESIXSell−108,694−0.01
≡CPIX – CUMBERLAND PHARMACEUTICALS IReduce 42.00%−144,109−0.01
≡NVNO – ENVVENO MEDICAL CORPORATIONSell−1,759,035−0.01
≡IRD – OPUS GENETICS INCReduce 58.00%−2,489,1580.01
≡IOVA – IOVANCE BIOTHERAPEUTICS INCSell−152,714−0.01
≡AXGN – AXOGEN INCReduce 11.00%−86,828−0.01
≡PALATIN TECHNOLOGIES INCReduce 12.00%−8,0550.00
Q4 2025filed Feb 17, 2640 new31 added17 reduced15 exited
≡ARCELLX INCReduce 41.00%−1,002,282−4.02
≡MRUS 10/21/22 P30 – MERUS N VSell−1,353,093−3.60
≡INSM – INSMED INCSell−702,130−2.86
≡AMLX – AMYLYX PHARMACEUTICALS INCReduce 7.00%−667,483−1.65
Q3 2025filed Nov 14, 2521 new28 added13 reduced14 exited
≡VERONA PHARMA PLCReduce 90.00%−4,983,503−17.25
≡SOLENO THERAPEUTICS INCSell−430,439−1.30
≡XBIPUT – SPDR SERIES TRUSTSell−300,000−0.90
≡EOLS – EVOLUS INCSell−2,474,843
Q2 2025filed Aug 14, 2524 new7 added27 reduced26 exited
≡AMICUS THERAPEUTICS INCReduce 65.00%−14,051,697−4.65
≡VERONA PHARMA PLCReduce 16.00%−1,055,7494.11
≡INTRA-CELLULAR THERAPIES INCSell−786,358−3.66
≡EWTX – EDGEWISE THERAPEUTICS INCReduce 29.00%−1,907,379−2.89
≡
Q1 2025filed Aug 6, 2519 new12 added27 reduced31 exited
≡IOVA – IOVANCE BIOTHERAPEUTICS INCReduce 43.00%−9,400,478−2.95
≡PCVX – VAXCYTE INCReduce 59.00%−1,011,850−2.88
≡NUVALENT INCReduce 38.00%−986,009−1.48
≡PRAX – PRAXIS PRECISION MEDICINES IReduce 26.00%−348,841−1.47
Q4 2024filed Feb 14, 2524 new9 added39 reduced33 exited
≡SOLENO THERAPEUTICS INCReduce 53.00%−1,703,936−1.59
≡BHVN – BIOHAVEN LTDSell−1,485,232−1.57
≡APPLIED THERAPEUTICS INCReduce 89.00%−7,145,000−1.42
≡APGE – APOGEE THERAPEUTICS INCReduce 48.00%−967,775−1.21
Q3 2024filed Nov 14, 2417 new20 added19 reduced19 exited
≡CEREVEL THERAPEUTICS HLDNG ISell−10,794,876−10.63
≡MDGL – MADRIGAL PHARMACEUTICALS INCSell−264,600−1.79
≡NBIX – NEUROCRINE BIOSCIENCES INCReduce 67.00%−437,681−1.64
≡SPRINGWORKS THERAPEUTICS INCReduce 58.00%−960,699−1.03
Q2 2024filed Aug 16, 2422 new17 added29 reduced24 exited
≡INHIBRX INCSell−4,256,104−2.60
≡FUSION PHARMACEUTICALS INCSell−6,825,395−2.55
≡MDT – MEDTRONIC PLCReduce 66.00%−938,898−1.25
≡SRPT – SAREPTA THERAPEUTICS INCSell−525,683−1.19
Q1 2024filed Aug 6, 2429 new34 added15 reduced18 exited
≡LIANBIOSell−57,558,451−5.74
≡CYMABAY THERAPEUTICS INCSell−4,024,400−2.12
≡RAYZEBIO INCSell−744,056−1.03
≡RAPT THERAPEUTICS INCReduce 43.00%−916,478−0.99
≡ARCELLX INC
Q4 2023filed Feb 26, 2423 new26 added17 reduced19 exited
≡IMVT – IMMUNOVANT INCReduce 39.00%−1,486,609−2.70
≡ARGX – ARGENX SESell−150,600−2.47
≡AKERO THERAPEUTICS INCReduce 40.00%−651,650−2.23
≡ALDX – ALDEYRA THERAPEUTICS INCReduce 24.00%−2,756,499−1.86
Q3 2023filed Nov 14, 2317 new21 added23 reduced15 exited
≡APELLIS PHARMACEUTICALS INCSell−812,037−2.14
≡REATA PHARMACEUTICALS INCSell−670,206−1.98
≡MDGL – MADRIGAL PHARMACEUTICALS INCReduce 59.00%−178,350−1.42
≡AMLX – AMYLYX PHARMACEUTICALS INCReduce 45.00%−2,185,046−1.40
Q2 2023filed Aug 24, 2318 new18 added26 reduced22 exited
≡PROMETHEUS BIOSCIENCES INCSell−1,272,694−4.03
≡REATA PHARMACEUTICALS INCReduce 69.00%−1,499,070−3.85
≡MDGL – MADRIGAL PHARMACEUTICALS INCReduce 53.00%−347,575−2.63
≡AMLX – AMYLYX PHARMACEUTICALS INCReduce 19.00%−1,160,725−2.18
≡VERONA PHARMA PLCSell−524,088−1.58
≡AKERO THERAPEUTICS INCSell−1,135,766−1.52
≡MEIRAGTX HLDGS PLCReduce 18.00%−2,300,000−1.47
≡AORT – ARTIVION INCReduce 15.00%−297,710−1.02
≡PEN – PENUMBRA INCReduce 50.00%−110,018−0.97
≡NBIX – NEUROCRINE BIOSCIENCES INCReduce 26.00%−119,000−0.95
≡CENTESSA PHARMACEUTICALS PLCReduce 6.00%−183,268−0.82
≡AQST – AQUESTIVE THERAPEUTICS INCReduce 80.00%−3,012,906−0.51
≡ALDX – ALDEYRA THERAPEUTICS INCReduce 20.00%−1,036,679−0.38
≡IRTC – IRHYTHM TECHNOLOGIES INCReduce 12.00%−15,000−0.26
≡CRVS – CORVUS PHARMACEUTICALS INCReduce 52.00%−746,154−0.20
≡PALVELLA THERAPEUTICS INC NEReduce 33.00%−128,806−0.20
≡JANX – JANUX THERAPEUTICS INCSell−292,686−0.20
≡TEM – TEMPUS AI INCSell−85,000−0.19
≡ADMA – ADMA BIOLOGICS INCReduce 23.00%−270,000−0.19
≡KYMR – KYMERA THERAPEUTICS INCReduce 59.00%−99,861−0.17
≡HTFL – HEARTFLOW INCSell−150,000−0.14
≡GOSS – GOSSAMER BIO INCReduce 18.00%−673,128−0.11
≡KRYS – KRYSTAL BIOTECH INCReduce 50.00%−17,500−0.10
≡SCPHARMACEUTICALS INCSell−583,142−0.09
≡VKTX – VIKING THERAPEUTICS INCSell−105,597−0.08
≡PYXS – PYXIS ONCOLOGY INCSell−1,178,307−0.07
≡SEPN – SEPTERNA INCReduce 20.00%−108,290−0.07
≡SPRYPUT – ARS PHARMACEUTICALS INCSell−200,000−0.06
≡TRIB – TRINITY BIOTECH PLCSell−1,790,000−0.05
≡LYRA THERAPEUTICS INCSell−229,382−0.04
≡QURE – UNIQURE NVSell−20,000−0.03
≡APYX – APYX MEDICAL CORPORATIONSell−150,000−0.01
−0.82
≡AORT – ARTIVION INCReduce 28.00%−773,703−0.73
≡PODD – INSULET CORPSell−60,387−0.69
≡BBNX – BETA BIONICS INCReduce 83.00%−1,315,664−0.68
≡DYN – DYNE THERAPEUTICS INCReduce 76.00%−1,706,946−0.58
≡CRL – CHARLES RIV LABS INTL INCSell−100,000−0.55
≡IMVT – IMMUNOVANT INCReduce 26.00%−550,000−0.51
≡EWTX – EDGEWISE THERAPEUTICS INCReduce 18.00%−844,055−0.46
≡ADMA – ADMA BIOLOGICS INCReduce 12.00%−150,000−0.38
≡RARE – ULTRAGENYX PHARMACEUTICAL INSell−270,000−0.35
≡VKTX – VIKING THERAPEUTICS INCReduce 72.00%−275,103−0.29
≡SYRE – SPYRE THERAPEUTICS INCReduce 20.00%−300,000−0.25
≡AXSM – AXSOME THERAPEUTICS INCReduce 25.00%−49,634−0.24
≡CAPRICOR THERAPEUTICS INCSell−650,000−0.23
≡GMED – GLOBUS MED INCSell−88,500−0.19
≡BBOT – HELIX ACQUISITION CORP IISell−398,000−0.15
≡AMICUS THERAPEUTICS INCReduce 14.00%−1,041,979−0.12
≡KYMR – KYMERA THERAPEUTICS INCReduce 19.00%−40,310−0.06
≡ATHA 04/16/21 P15 – ATHIRA PHARMA INCSell−5,402,964−0.06
≡LYRA THERAPEUTICS INCReduce 10.00%−25,768−0.04
≡CAPRICOR THERAPEUTICS INCSell−100,000−0.04
≡FBRX – FORTE BIOSCIENCES INCSell−68,192−0.03
≡BDSX – BIODESIX INCSell−2,173,880−0.02
≡KALA BIO INCSell−55,227−0.01
SOLENO THERAPEUTICS INC
Reduce 71.00%
−1,076,163
−2.50
≡IOVA – IOVANCE BIOTHERAPEUTICS INCSell−12,711,788−1.50
≡ALDX – ALDEYRA THERAPEUTICS INCReduce 56.00%−5,224,220−1.32
≡ARGX – ARGENX SESell−59,510−1.24
≡MERUS N VSell−690,485−1.03
≡CENTESSA PHARMACEUTICALS PLCReduce 62.00%−1,893,460−1.00
≡PCVX – VAXCYTE INCSell−706,567−0.94
≡EOLS – EVOLUS INCReduce 40.00%−1,654,299−0.93
≡ARCELLX INCReduce 15.00%−448,478−0.88
≡AXSM – AXSOME THERAPEUTICS INCReduce 44.00%−156,573−0.71
≡JANX – JANUX THERAPEUTICS INCReduce 70.00%−677,726−0.68
≡MDGL – MADRIGAL PHARMACEUTICALS INCSell−46,500−0.54
≡SYRE – SPYRE THERAPEUTICS INCReduce 34.00%−783,827−0.49
≡IMVT – IMMUNOVANT INCReduce 25.00%−706,182−0.48
≡DXCM – DEXCOM INCSell−178,000−0.43
≡EWTXCALL – EDGEWISE THERAPEUTICS INCSell−500,000−0.39
≡ACRV – ACRIVON THERAPEUTICS INCSell−5,360,858−0.38
≡CARGO THERAPEUTICS INCSell−2,431,085−0.35
≡NUVALENT INCReduce 16.00%−258,788−0.30
≡EYPT – EYEPOINT PHARMACEUTICALS INCSell−1,537,274−0.29
≡IRON – DISC MEDICINE INCSell−150,000−0.26
≡CTNM – CONTINEUM THERAPEUTICS INCReduce 51.00%−741,763−0.25
≡ADPT – ADAPTIVE BIOTECHNOLOGIES CORSell−930,972−0.24
≡OCUL – OCULAR THERAPEUTIX INCSell−915,775−0.24
≡DELCATH SYS INCSell−462,422−0.21
≡ZYME – ZYMEWORKS INCReduce 32.00%−589,398−0.21
≡RAPT THERAPEUTICS INCSell−4,418,947−0.19
≡KESTRA MED TECHNOLOGIES LTDSell−200,000−0.18
≡PRAX – PRAXIS PRECISION MEDICINES IReduce 23.00%−227,973−0.17
≡XENE – XENON PHARMACEUTICALS INCReduce 38.00%−124,533−0.16
≡ONKURE THERAPEUTICS INCSell−1,004,439−0.15
≡AVTX – AVALO THERAPEUTICS INCReduce 73.00%−380,333−0.12
≡AQST – AQUESTIVE THERAPEUTICS INCReduce 41.00%−1,536,788−0.12
≡VRDN – VIRIDIAN THERAPEUTICS INCReduce 32.00%−212,155−0.09
≡IKT – INHIBIKASE THERAPEUTICS INCReduce 8.00%−492,707−0.08
≡MREO – MEREO BIOPHARMA GROUP PLCSell−876,961−0.07
≡VKTX – VIKING THERAPEUTICS INCReduce 25.00%−128,305−0.07
≡LYRA – LYRA THERAPEUTICS INCSell−12,757,562−0.06
≡CELC – CELCUITY INCReduce 31.00%−729,071−0.06
≡ATHIRA PHARMA INCSell−5,402,964−0.05
≡KALA BIO INCReduce 80.00%−222,383−0.05
≡AVR – ANTERIS TECHNOLOGIES GLOBALReduce 20.00%−434,870−0.04
≡TRAWS PHARMA INCSell−421,781−0.03
≡RCKT – ROCKET PHARMACEUTICALS INCSell−140,726−0.03
≡PODD – INSULET CORPReduce 16.00%−11,2100.02
≡CGEM – CULLINAN THERAPEUTICS INCSell−80,100−0.02
≡INBX – INHIBRX BIOSCIENCES INCReduce 8.00%−86,134−0.02
≡APPLIED THERAPEUTICS INCSell−860,000−0.01
≡NBTX – NANOBIOTIXSell−105,053−0.01
≡CENTESSA PHARMACEUTICALS PLCReduce 52.00%−3,308,825−1.35
≡CARGO THERAPEUTICS INCReduce 34.00%−1,251,919−1.09
≡PRAXCALL – PRAXIS PRECISION MEDICINES ISell−500,000−1.05
≡PODD – INSULET CORPReduce 69.00%−160,672−0.98
≡RYTM – RHYTHM PHARMACEUTICALS INCReduce 31.00%−1,132,028−0.83
≡INTRA-CELLULAR THERAPIES INCReduce 39.00%−501,9700.74
≡VKTX – VIKING THERAPEUTICS INCReduce 49.00%−486,889−0.66
≡PRCT – PROCEPT BIOROBOTICS CORPSell−290,659−0.64
≡NTRA – NATERA INCSell−125,000−0.54
≡PTGX – PROTAGONIST THERAPEUTICS INCReduce 14.00%−180,3910.53
≡PEN – PENUMBRA INCSell−73,338−0.47
≡ARCELLX INCReduce 16.00%−552,410−0.47
≡SEPN – SEPTERNA INCSell−750,000−0.47
≡VRDN – VIRIDIAN THERAPEUTICS INCReduce 56.00%−826,846−0.46
≡ORKA – ORUKA THERAPEUTICS INCSell−845,567−0.45
≡ARVN – ARVINAS INCSell−740,749−0.39
≡MRUS 10/21/22 P30 – MERUS N VSell−300,000−0.34
≡CGON – CG ONCOLOGY INCSell−419,450−0.33
≡SYRE – SPYRE THERAPEUTICS INCReduce 10.00%−261,451−0.31
≡EW – EDWARDS LIFESCIENCES CORPSell−145,000−0.29
≡TARS – TARSUS PHARMACEUTICALS INCSell−186,662−0.28
≡CRNX – CRINETICS PHARMACEUTICALS INSell−184,525−0.26
≡RAPT 05/21/21 C35 – RAPT THERAPEUTICS INCSell−5,880,000−0.25
≡INARI MED INCSell−178,797−0.25
≡AKERO THERAPEUTICS INCReduce 33.00%−392,6320.24
≡EOLS – EVOLUS INCReduce 20.00%−1,016,7040.21
≡ISRG – INTUITIVE SURGICAL INCReduce 36.00%−22,500−0.19
≡ZENAS BIOPHARMA INCSell−744,035−0.17
≡IRTC – IRHYTHM TECHNOLOGIES INCSell−65,153−0.16
≡RAPP – RAPPORT THERAPEUTICS INCSell−311,551−0.15
≡CERIBELL INCSell−180,546−0.13
≡ARGX – ARGENX SEReduce 12.00%−7,9610.12
≡VERU – VERU INCSell−6,483,157−0.11
≡PERSPECTIVE THERAPEUTICS INCSell−1,190,263−0.10
≡LINEAGE CELL THERAPEUTICS INSell−7,236,843−0.10
≡RCKT – ROCKET PHARMACEUTICALS INCReduce 63.00%−237,858−0.10
≡ATHA 04/16/21 P15 – ATHIRA PHARMA INCSell−5,402,964−0.09
≡PEPG – PEPGEN INCSell−829,536−0.09
≡IMMUNITYBIO INCSell−1,221,734−0.09
≡BCYC – BICYCLE THERAPEUTICS PLCSell−197,108−0.08
≡AXSM – AXSOME THERAPEUTICS INCReduce 47.00%−308,967−0.06
≡ZYME – ZYMEWORKS INCReduce 12.00%−265,348−0.06
≡VRCA – VERRICA PHARMACEUTICALS INCSell−3,249,669−0.06
≡FBRX – FORTE BIOSCIENCES INCSell−95,742−0.06
≡NRIX – NURIX THERAPEUTICS INCReduce 10.00%−33,061−0.04
≡TRIB – TRINITY BIOTECH PLCSell−1,790,000−0.04
≡MREO – MEREO BIOPHARMA GROUP PLCReduce 19.00%−208,551−0.03
≡FULC – FULCRUM THERAPEUTICS INCSell−238,000−0.03
≡AMICUS THERAPEUTICS INCReduce 11.00%−2,781,425−0.02
≡NVAXPUT – NOVAVAX INCSell−100,000−0.02
≡BBOT – HELIX ACQUISITION CORP IIReduce 20.00%−102,0000.02
≡OCUL – OCULAR THERAPEUTIX INCReduce 15.00%−162,720−0.01
≡PYXS – PYXIS ONCOLOGY INCSell−188,462−0.01
≡NBTX – NANOBIOTIXReduce 61.00%−161,040−0.01
≡
VKTX – VIKING THERAPEUTICS INC
Reduce 41.00%
−704,093
−1.19
≡PCVX – VAXCYTE INCReduce 15.00%−309,191−1.07
≡NUVALENT INCReduce 12.00%−359,258−0.87
≡XBIPUT – SPDR SER TRSell−400,000−0.84
≡IOVA – IOVANCE BIOTHERAPEUTICS INCReduce 17.00%−4,505,443−0.84
≡TARS – TARSUS PHARMACEUTICALS INCReduce 86.00%−1,109,754−0.62
≡VRDN – VIRIDIAN THERAPEUTICS INCReduce 47.00%−1,326,157−0.58
≡CRNX – CRINETICS PHARMACEUTICALS INReduce 75.00%−540,173−0.53
≡INSTIL BIO INCSell−345,545−0.49
≡LIVN – LIVANOVA PLCSell−429,000−0.48
≡SPRINGWORKS THERAPEUTICS INCSell−692,263−0.47
≡MDT – MEDTRONIC PLCSell−245,332−0.47
≡INTRA-CELLULAR THERAPIES INCReduce 21.00%−333,8870.42
≡IRON – DISC MEDICINE INCSell−387,017−0.40
≡ARCELLX INCReduce 11.00%−409,7810.39
≡OCUL – OCULAR THERAPEUTIX INCReduce 68.00%−2,245,973−0.36
≡MERUS N VSell−300,000−0.32
≡ICLR – ICON PLCSell−44,353−0.27
≡ARQT – ARCUTIS BIOTHERAPEUTICS INCSell−1,358,500−0.27
≡CGON – CG ONCOLOGY INCReduce 43.00%−314,245−0.26
≡TYRA – TYRA BIOSCIENCES INCSell−511,226−0.25
≡ZENAS BIOPHARMA INCReduce 35.00%−400,000−0.24
≡RCKT – ROCKET PHARMACEUTICALS INCReduce 59.00%−553,267−0.23
≡ARGX – ARGENX SEReduce 43.00%−51,368−0.23
≡XNCR – XENCOR INCSell−527,671−0.22
≡ROIV – ROIVANT SCIENCES LTDSell−847,745−0.21
≡AVBP – ARRIVENT BIOPHARMA INCSell−415,000−0.21
≡DYN – DYNE THERAPEUTICS INCReduce 24.00%−174,867−0.20
≡ORKA – ORUKA THERAPEUTICS INCReduce 32.00%−389,620−0.19
≡EXACT SCIENCES CORPSell−125,000−0.18
≡RAPP – RAPPORT THERAPEUTICS INCReduce 58.00%−436,632−0.17
≡PEPG – PEPGEN INCReduce 41.00%−580,902−0.17
≡ALLO – ALLOGENE THERAPEUTICS INCSell−2,725,000−0.16
≡SYRE – SPYRE THERAPEUTICS INCReduce 10.00%−297,824−0.16
≡VRCA – VERRICA PHARMACEUTICALS INCReduce 54.00%−3,849,513−0.16
≡VERONA PHARMA PLCSell−250,000−0.15
≡VERONA PHARMA PLCSell−250,000−0.15
≡ARVN – ARVINAS INCReduce 28.00%−287,000−0.15
≡NBIX – NEUROCRINE BIOSCIENCESReduce 53.00%−112,178−0.15
≡AKERO THERAPEUTICS INCReduce 31.00%−529,214−0.14
≡AMICUS THERAPEUTICS INCReduce 14.00%−3,811,504−0.13
≡FLNAPUT – CASSAVA SCIENCES INCSell−183,000−0.11
≡FULCCALL – FULCRUM THERAPEUTICS INCSell−1,500,000−0.11
≡PRCT – PROCEPT BIOROBOTICS CORPReduce 8.00%−25,0000.10
≡XENE – XENON PHARMACEUTICALS INCReduce 38.00%−199,606−0.09
≡DTIL – PRECISION BIOSCIENCES INCSell−426,293−0.08
≡ABSI – ABSCI CORPORATIONSell−700,000−0.06
≡NTRA – NATERA INCReduce 43.00%−95,000−0.05
≡ATHIRA PHARMA INCSell−5,402,964−0.05
≡ASNSUSD – X4 PHARMACEUTICALS INCSell−3,545,454−0.05
≡NVNO – ENVVENO MEDICAL CORPORATIONSell−694,315−0.05
≡BCYC – BICYCLE THERAPEUTICS PLCReduce 23.00%−58,886−0.05
≡NBTX – NANOBIOTIXReduce 52.00%−288,973−0.05
≡KYMR – KYMERA THERAPEUTICS INCSell−46,213−0.05
≡AXSM – AXSOME THERAPEUTICS INCReduce 15.00%−118,7700.04
≡ADMA – ADMA BIOLOGICS INCReduce 16.00%−169,920−0.03
≡STRUCTURE THERAPEUTICS INCSell−34,852−0.03
≡PYXS – PYXIS ONCOLOGY INCReduce 63.00%−320,000−0.03
≡PTGX – PROTAGONIST THERAPEUTICS INCReduce 7.00%−102,9010.03
≡FATE – FATE THERAPEUTICS INCSell−345,575−0.03
≡SINGULAR GENOMICS SYSTEMS INSell−50,896−0.02
≡KYTX – KYVERNA THERAPEUTICS INCSell−150,000−0.02
≡INSM – INSMED INCReduce 20.00%−36,000−0.01
≡IMVT – IMMUNOVANT INCReduce 10.00%−239,5630.01
≡SYRS – SYROS PHARMACEUTICALS INCSell−116,754−0.01
≡VERU – VERU INCReduce 11.00%−800,000−0.00
≡CAREMAX INCSell−100,000−0.00
≡CAREMAX INCSell−60,000−0.00
≡
CRNX – CRINETICS PHARMACEUTICALS IN
Reduce 51.00%
−751,505
−0.81
≡NTRA – NATERA INCReduce 58.00%−310,000−0.79
≡BBIO – BRIDGEBIO PHARMA INCSell−1,215,346−0.74
≡MDT – MEDTRONIC PLCReduce 50.00%−245,333−0.46
≡EOLS – EVOLUS INCReduce 7.00%−397,1760.33
≡CGEM – CULLINAN THERAPEUTICS INCSell−749,916−0.32
≡ADMA – ADMA BIOLOGICS INCReduce 62.00%−1,710,800−0.30
≡RCKT – ROCKET PHARMACEUTICALS INCReduce 25.00%−314,746−0.28
≡TEM – TEMPUS AI INCSell−275,000−0.23
≡IRON – DISC MEDICINE INCReduce 30.00%−166,420−0.20
≡ENGN – ENGENE HOLDINGS INCSell−800,000−0.18
≡SPRY – ARS PHARMACEUTICALS INCSell−867,319−0.18
≡BCYC – BICYCLE THERAPEUTICS PLCReduce 55.00%−316,006−0.16
≡KALVISTA PHARMACEUTICALS INCSell−500,000−0.14
≡RXRX – RECURSION PHARMACEUTICALS INSell−769,230−0.14
≡TYRA – TYRA BIOSCIENCES INCReduce 49.00%−496,141−0.13
≡IMVTCALL – IMMUNOVANT INCSell−200,000−0.13
≡XENE – XENON PHARMACEUTICALS INCReduce 10.00%−58,326−0.11
≡CABA – CABALETTA BIO INCSell−585,045−0.11
≡SKYE BIOSCIENCE INCSell−500,000−0.10
≡ARQT – ARCUTIS BIOTHERAPEUTICS INCReduce 13.00%−200,000−0.08
≡FHTX – FOGHORN THERAPEUTICS INCSell−544,000−0.08
≡ISRG – INTUITIVE SURGICAL INCReduce 6.00%−3,681−0.06
≡IRTC – IRHYTHM TECHNOLOGIES INCReduce 36.00%−12,614−0.06
≡XBI – SPDR SER TRSell−22,665−0.05
≡MREO – MEREO BIOPHARMA GROUP PLCReduce 35.00%−437,528−0.04
≡REVANCE THERAPEUTICS INCSell−600,000−0.04
≡FBRX – FORTE BIOSCIENCES INCReduce 97.00%−3,169,617−0.03
≡EGRX – EAGLE PHARMACEUTICALS INCSell−173,365−0.02
≡VBI VACCINES INC CDASell−1,261,710−0.02
≡TCMD – TACTILE SYS TECHNOLOGY INCSell−62,639−0.02
≡AXGN – AXOGEN INCSell−30,421−0.01
≡CAREMAX INCReduce 18.00%−22,643−0.00
≡SINGULAR GENOMICS SYSTEMS INReduce 28.00%−20,0000.00
≡
NUVALENT INC
Reduce 8.00%
−234,377
1.00
≡AXSM – AXSOME THERAPEUTICS INCReduce 58.00%−646,230−0.65
≡VRDN – VIRIDIAN THERAPEUTICS INCReduce 55.00%−2,025,271−0.61
≡LANDOS BIOPHARMA INCSell−1,486,991−0.56
≡TMCI – TREACE MED CONCEPTS INCSell−2,304,954−0.53
≡VKTX – VIKING THERAPEUTICS INCReduce 27.00%−272,721−0.51
≡AUTL – AUTOLUS THERAPEUTICS PLCSell−4,330,745−0.48
≡IMVT – IMMUNOVANT INCReduce 35.00%−1,039,426−0.45
≡SPRINGWORKS THERAPEUTICS INCReduce 27.00%−609,500−0.45
≡CGON – CG ONCOLOGY INCReduce 44.00%−570,410−0.44
≡IRON – DISC MEDICINE INCReduce 41.00%−386,429−0.42
≡BHVN – BIOHAVEN LTDReduce 14.00%−239,815−0.41
≡CABA – CABALETTA BIO INCReduce 66.00%−1,131,615−0.41
≡IRTC – IRHYTHM TECHNOLOGIES INCReduce 86.00%−210,000−0.41
≡RVMD – REVOLUTION MEDICINES INCSell−618,885−0.35
≡ABBV – ABBVIE INCSell−106,500−0.34
≡IRONPUT – DISC MEDICINE INCSell−300,000−0.33
≡MLTX – MOONLAKE IMMUNOTHERAPEUTICSSell−339,012−0.30
≡TCMD – TACTILE SYS TECHNOLOGY INCReduce 93.00%−840,446−0.24
≡ARVN – ARVINAS INCReduce 17.00%−208,854−0.23
≡MDGL – MADRIGAL PHARMACEUTICALS INCReduce 38.00%−165,353−0.22
≡AXGN – AXOGEN INCReduce 98.00%−1,523,508−0.21
≡NBIX – NEUROCRINE BIOSCIENCES INCReduce 19.00%−154,5000.21
≡VERONA PHARMA PLCReduce 35.00%−1,327,851−0.21
≡RCKT – ROCKET PHARMACEUTICALS INCReduce 31.00%−554,471−0.20
≡RAPT THERAPEUTICS INCSell−1,223,472−0.19
≡MORPHIC HLDG INCSell−288,221−0.18
≡NTRA – NATERA INCReduce 30.00%−227,2250.17
≡PRAX – PRAXIS PRECISION MEDICINES IReduce 9.00%−71,359−0.13
≡XENE – XENON PHARMACEUTICALS INCReduce 35.00%−308,952−0.12
≡ENGN – ENGENE HOLDINGS INCReduce 20.00%−198,888−0.11
≡COGT – COGENT BIOSCIENCES INCSell−883,333−0.10
≡IMMUNITYBIO INCSell−1,052,887−0.10
≡MGNX – MACROGENICS INCSell−378,327−0.10
≡AMLXCALL – AMYLYX PHARMACEUTICALS INCSell−1,679,125−0.08
≡XBIPUT – SPDR SER TRSell−50,000−0.08
≡ESTABLISHMENT LABS HLDGS INCSell−82,299−0.07
≡NAMS – NEWAMSTERDAM PHARMA COMPANYSell−175,000−0.07
≡EWTX – EDGEWISE THERAPEUTICS INCReduce 20.00%−463,2290.07
≡APPLIED THERAPEUTICS INCSell−500,000−0.06
≡AGIOCALL – AGIOS PHARMACEUTICALS INCSell−100,000−0.05
≡ISRG – INTUITIVE SURGICAL INCReduce 39.00%−40,000−0.05
≡NVAXPUT – NOVAVAX INCReduce 86.00%−600,000−0.03
≡BBIO – BRIDGEBIO PHARMA INCReduce 14.00%−196,687−0.02
≡SINGULAR GENOMICS SYSTEMS INSell−2,126,893−0.02
≡KURA ONCOLOGY INCSell−48,200−0.02
≡AMLX – AMYLYX PHARMACEUTICALS INCSell−300,000−0.01
≡DTIL – PRECISION BIOSCIENCES INCReduce 11.00%−54,190−0.01
≡ADMA – ADMA BIOLOGICS INCReduce 57.00%−3,662,3690.00
Reduce 13.00%
−611,253
−0.84
≡BBIO – BRIDGEBIO PHARMA INCReduce 19.00%−336,900−0.81
≡AMLX – AMYLYX PHARMACEUTICALS INCReduce 84.00%−1,569,125−0.60
≡CABA – CABALETTA BIO INCReduce 14.00%−286,398−0.50
≡ABBV – ABBVIE INCReduce 55.00%−131,500−0.48
≡XENE – XENON PHARMACEUTICALS INCReduce 19.00%−208,540−0.46
≡ASND – ASCENDIS PHARMAA/SSell−132,176−0.37
≡MIRM – MIRUM PHARMACEUTICALS INCSell−534,942−0.35
≡IRON – DISC MEDICINE INCReduce 8.00%−83,179−0.30
≡TNGX – TANGO THERAPEUTICS INCSell−1,111,870−0.25
≡RVMD – REVOLUTION MEDICINES INCReduce 24.00%−199,997−0.18
≡OLMA – OLEMA PHARMACEUTICALS INCSell−539,831−0.17
≡TERNS PHARMACEUTICALS INCSell−1,075,000−0.16
≡RGNX – REGENXBIO INCSell−342,408−0.14
≡TVTX – TRAVERE THERAPEUTICS INCSell−400,000−0.08
≡ACAD – ACADIA PHARMACEUTICALS INCSell−101,000−0.07
≡CYTK – CYTOKINETICS INCSell−30,317−0.06
≡XBIPUT – SPDR SER TRReduce 97.00%−1,850,0000.05
≡KRONOS BIO INCSell−1,752,745−0.05
≡NVAXPUT – NOVAVAX INCReduce 50.00%−700,000−0.05
≡COGT – COGENT BIOSCIENCES INCReduce 21.00%−239,625−0.04
≡CAREMAX INCSell−3,679,284−0.04
≡MGNX – MACROGENICS INCReduce 38.00%−233,605−0.03
≡AMBRX BIOPHARMA INCSell−78,811−0.03
≡NTRA – NATERA INCReduce 11.00%−93,0000.02
≡VBI VACCINES INC CDAReduce 9.00%−119,645−0.00
≡CYPH – LEAP THERAPEUTICS INCSell−44,971−0.00
≡BCABGBP – BIOATLA INCSell−73,000−0.00
≡EYPTPUT – EYEPOINT PHARMACEUTICALS INCSell−750,000−0.00
≡ROIV – ROIVANT SCIENCES LTDSell−3,819,456−1.49
≡HRMY – HARMONY BIOSCIENCES HLDGS INSell−996,306−1.09
≡AMLX – AMYLYX PHARMACEUTICALS INCReduce 30.00%−819,748−1.03
≡PCVX – VAXCYTE INCReduce 19.00%−254,265−0.76
≡RVMD – REVOLUTION MEDICINES INCReduce 38.00%−502,913−0.70
≡TNGX – TANGO THERAPEUTICS INCReduce 54.00%−1,307,098−0.66
≡COGT – COGENT BIOSCIENCES INCReduce 51.00%−1,186,512−0.60
≡RLAY – RELAY THERAPEUTICS INCSell−1,943,097−0.55
≡TMCI – TREACE MED CONCEPTS INCReduce 32.00%−583,655−0.45
≡ESTABLISHMENT LABS HLDGS INCReduce 70.00%−195,384−0.41
≡PTGX – PROTAGONIST THERAPEUTICS INCReduce 64.00%−671,013−0.39
≡MIRM – MIRUM PHARMACEUTICALS INCReduce 20.00%−137,100−0.36
≡BMEA – BIOMEA FUSIONSell−716,441−0.33
≡PROTHENA CORP PLCSell−165,615−0.27
≡OUTSET MED INCSell−661,977−0.24
≡ADMA – ADMA BIOLOGICS INCReduce 8.00%−550,950−0.18
≡AKERO THERAPEUTICS INCSell−800,000−0.18
≡SOMALOGIC INCSell−1,500,000−0.12
≡SRPTCALL – SAREPTA THERAPEUTICS INCSell−100,000−0.10
≡POINT BIOPHARMA GLOBAL INCSell−800,000−0.09
≡ARQTPUT – ARCUTIS BIOTHERAPEUTICS INCSell−300,000−0.09
≡NVNO – ENVVENO MEDICAL CORPORATIONReduce 20.00%−158,300−0.07
≡ACELYRIN INCSell−200,000−0.07
≡ZYME – ZYMEWORKS INCReduce 26.00%−371,316−0.06
≡89BIO INCSell−400,000−0.05
≡ACRSPUT – ACLARIS THERAPEUTICS INCSell−500,000−0.05
≡AXGN – AXOGEN INCReduce 8.00%−67,518−0.02
≡SINGULAR GENOMICS SYSTEMS INReduce 10.00%−236,321−0.01
≡VKTXCALL – VIKING THERAPEUTICS INCSell−300,000−0.01
≡APELLIS PHARMACEUTICALS INCSell−100,000−0.00
≡MOTUS GI HLDGS INCSell−90,027−0.00
≡EQRX INCSell−250,000−0.00
≡
VIR – VIR BIOTECHNOLOGY INC
Sell
−1,958,264
−1.39
≡IOVA – IOVANCE BIOTHERAPEUTICS INCReduce 15.00%−2,073,472−1.04
≡TMCI – TREACE MED CONCEPTS INCReduce 17.00%−383,190−0.84
≡ILMN – ILLUMINA INCSell−145,000−0.79
≡MIRATI THERAPEUTICS INCSell−719,103−0.75
≡VRDN – VIRIDIAN THERAPEUTICS INCReduce 43.00%−765,181−0.71
≡BMRN – BIOMARIN PHARMACEUTICAL INCSell−263,207−0.66
≡XENE – XENON PHARMACEUTICALS INCReduce 50.00%−605,877−0.66
≡PTGX – PROTAGONIST THERAPEUTICS INCReduce 28.00%−415,488−0.59
≡VERONA PHARMA PLCReduce 9.00%−389,919−0.51
≡INTRA-CELLULAR THERAPIES INCSell−245,800−0.45
≡ADMA – ADMA BIOLOGICS INCReduce 41.00%−4,915,936−0.44
≡ESTABLISHMENT LABS HLDGS INCReduce 35.00%−147,241−0.39
≡OUTSET MED INCReduce 27.00%−240,383−0.33
≡ZYME – ZYMEWORKS INCReduce 40.00%−970,109−0.30
≡TERNS PHARMACEUTICALS INCSell−1,075,000−0.27
≡NTRA – NATERA INCReduce 46.00%−187,091−0.25
≡AXGN – AXOGEN INCReduce 40.00%−588,924−0.24
≡CRNX – CRINETICS PHARMACEUTICALS INReduce 35.00%−683,2050.24
≡VKTX – VIKING THERAPEUTICS INCSell−441,147−0.21
≡IVERIC BIO INCSell−168,000−0.19
≡RAPT THERAPEUTICS INCReduce 16.00%−367,835−0.17
≡COGT – COGENT BIOSCIENCES INCReduce 13.00%−350,000−0.16
≡AKERO THERAPEUTICS INCReduce 17.00%−321,2500.11
≡PROTHENA CORP PLCReduce 10.00%−19,000−0.10
≡QTRX – QUANTERIX CORPSell−130,000−0.08
≡CYPH – LEAP THERAPEUTICS INCReduce 92.00%−541,762−0.05
≡PCVX – VAXCYTE INCReduce 17.00%−271,371−0.05
≡MIRATI THERAPEUTICS INCSell−200,000−0.02
≡VERONA PHARMA PLCSell−500,000−0.02
≡NBTX – NANOBIOTIXReduce 48.00%−504,7340.01
≡XBIPUT – SPDR SER TRSell−150,000−0.00
≡CABA – CABALETTA BIO INCReduce 27.00%−412,509−0.00
≡BTAIEURCALL – BIOXCEL THERAPEUTICS INCSell−439,500−0.00
≡
BMRN – BIOMARIN PHARMACEUTICAL INC
Reduce 61.00%
−409,853
−1.27
≡SNY – SANOFISell−768,101−1.23
≡BELLUS HEALTH INC NEWSell−4,952,538−1.05
≡MIRATI THERAPEUTICS INCReduce 54.00%−855,031−0.98
≡OBIO – ORCHESTRA BIOMED HLDGS INCReduce 10.00%−225,358−0.90
≡SRPT – SAREPTA THERAPEUTICS INCReduce 69.00%−179,784−0.79
≡CRNX – CRINETICS PHARMACEUTICALS INReduce 45.00%−1,607,950−0.67
≡NTRA – NATERA INCReduce 43.00%−301,945−0.59
≡XENE – XENON PHARMACEUTICALS INCReduce 33.00%−608,797−0.57
≡TERNS PHARMACEUTICALS INCSell−1,350,000−0.47
≡VBI VACCINES INC CDASell−52,335,002−0.47
≡RAIN ONCOLOGY INCSell−1,648,215−0.43
≡SPRINGWORKS THERAPEUTICS INCReduce 26.00%−541,921−0.41
≡ISRG – INTUITIVE SURGICAL INCSell−50,000−0.38
≡CTKB – CYTEK BIOSCIENCES INCSell−1,289,534−0.35
≡LRMR – LARIMAR THERAPEUTICS INCSell−2,280,709−0.31
≡ZYME – ZYMEWORKS INCReduce 28.00%−962,266−0.30
≡MORPHIC HLDG INCSell−256,737−0.29
≡VKTX – VIKING THERAPEUTICS INCReduce 49.00%−430,600−0.22
≡BELLEROPHON THERAPEUTICS INCSell−930,000−0.22
≡HILLEVAX INCSell−406,024−0.20
≡TMCI – TREACE MED CONCEPTS INCReduce 9.00%−225,000−0.17
≡IVERIC BIO INCReduce 66.00%−332,000−0.17
≡AVADEL PHARMACEUTICALS PLCSell−590,000−0.16
≡VERU – VERU INCReduce 98.00%−4,208,334−0.14
≡LANDOS BIOPHARMA INCSell−14,869,915−0.13
≡TCMD – TACTILE SYS TECHNOLOGY INCReduce 6.00%−37,5000.12
≡IOVA – IOVANCE BIOTHERAPEUTICS INCReduce 8.00%−1,303,3250.09
≡ESTABLISHMENT LABS HLDGS INCReduce 9.00%−42,933−0.09
≡ADC THERAPEUTICS SASell−1,495,805−0.09
≡PHENOMEX INCSell−2,506,442−0.09
≡ASNSUSD – X4 PHARMACEUTICALS INCReduce 22.00%−1,000,0000.08
≡LEAP THERAPEUTICS INCSell−6,726,496−0.07
≡BBIO – BRIDGEBIO PHARMA INCReduce 8.00%−158,100−0.06
≡SINGULAR GENOMICS SYSTEMS INReduce 28.00%−919,061−0.06
≡TYRA – TYRA BIOSCIENCES INCReduce 27.00%−134,403−0.06
≡AORT – ARTIVION INCReduce 14.00%−154,5080.04
≡DRIOEUR – DARIOHEALTH CORPSell−313,869−0.04
≡CLOV – CLOVER HEALTH INVESTMENTS COSell−1,500,000−0.04
≡ATHENEX INCSell−776,623−0.03
≡TARA – PROTARA THERAPEUTICS INCSell−290,051−0.03
≡PROTHENA CORP PLCReduce 22.00%−53,0310.02
≡OUTSET MED INCReduce 17.00%−187,067−0.02
≡PEAR THERAPEUTICS INCSell−900,548−0.01