| Hist | Stock | Activity | Share change | % change to portfolio |
|---|---|---|---|---|
| Q1 2026filed May 29, 2620 new17 added21 reduced42 exited | ||||
| ≡ | CENTESSA PHARMACEUTICALS PLC | Add 80.00% | 2,341,269 | 2.78 |
| ≡ | ASND – ASCENDIS PHARMA A/S | Add 42.00% | 450,000 | 2.73 |
| ≡ | XBIPUT – SPDR SERIES TRUST | Sell | −1,100,000 | −2.39 |
| ≡ | EXACT SCIENCES CORP | Sell | −1,200,487 | −2.17 |
| ≡ | SYRE – SPYRE THERAPEUTICS INC | Add 23.00% | 714,000 | 1.94 |
| ≡ | ARCELLX INC | Sell | −1,466,071 | −1.70 |
| ≡ | BSX – BOSTON SCIENTIFIC CORP | Sell | −979,000 | −1.66 |
| ≡ | AMICUS THERAPEUTICS INC | Sell | −6,370,851 | −1.62 |
| ≡ | RLAY – RELAY THERAPEUTICS INC | Add 412.00% | 7,847,896 | 1.61 |
| ≡ | ASTRIA THERAPEUTICS INC | Sell | −6,485,420 | −1.51 |
| ≡ | VRDN – VIRIDIAN THERAPEUTICS INC | Reduce 62.00% | −1,871,874 | −1.24 |
| ≡ | MRNAPUT – MODERNA INC | Buy | 1,000,000 | 0.99 |
| ≡ | BCRX – BIOCRYST PHARMACEUTICALS INC | Add 135.00% | 4,271,504 | 0.94 |
| ≡ | RYTM – RHYTHM PHARMACEUTICALS INC | Reduce 7.00% | −172,596 | −0.82 |
| ≡ | DHR – DANAHER CORPORATION | Sell | −200,000 | −0.82 |
| ≡ | IONS – IONIS PHARMACEUTICALS INC | Buy | 504,000 | 0.74 |
| ≡ | DAWNGBX – DAY ONE BIOPHARMACEUTICALS I | Buy | 1,755,799 | 0.74 |
| ≡ | BLTE – BELITE BIO INC | Reduce 63.00% | −262,260 | −0.71 |
| ≡ | NBIX – NEUROCRINE BIOSCIENCES INC | Reduce 80.00% | −266,000 | −0.67 |
| ≡ | CIDARA THERAPEUTICS INC | Sell | −165,131 | −0.65 |
| ≡ | IRON – DISC MEDICINE INC | Sell | −450,743 | −0.64 |
| ≡ | DAMORA THERAPEUTICS INC | Buy | 1,223,000 | 0.62 |
| ≡ | PEN – PENUMBRA INC | Sell | −110,529 | −0.61 |
| ≡ | APGE – APOGEE THERAPEUTICS INC | Reduce 34.00% | −790,267 | −0.60 |
| ≡ | CRVS – CORVUS PHARMACEUTICALS INC | Add 231.00% | 1,600,000 | 0.56 |
| ≡ | CAI – CARIS LIFE SCIENCES INC | Sell | −1,136,206 | −0.55 |
| ≡ | RAPT THERAPEUTICS INC | Sell | −825,890 | −0.50 |
| ≡ | PALVELLA THERAPEUTICS INC NE | Sell | −266,287 | −0.50 |
| ≡ | RVMD – REVOLUTION MEDICINES INC | Buy | 258,600 | 0.49 |
| ≡ | OMDA – OMADA HEALTH INC | Reduce 67.00% | −1,610,000 | −0.48 |
| ≡ | DYN – DYNE THERAPEUTICS INC | Add 34.00% | 1,189,895 | 0.44 |
| ≡ | PTGX – PROTAGONIST THERAPEUTICS INC | Reduce 9.00% | −119,546 | 0.43 |
| ≡ | SAB BIOTHERAPEUTICS INC | Add 701.00% | 5,628,533 | 0.43 |
| ≡ | KOD – KODIAK SCIENCES INC | Sell | −848,900 | −0.42 |
| ≡ | DBV TECHNOLOGIES S A | Buy | 964,391 | 0.39 |
| ≡ | BIIB – BIOGEN INC | Sell | −124,000 | −0.39 |
| ≡ | ALDX – ALDEYRA THERAPEUTICS INC | Sell | −4,185,632 | −0.39 |
| ≡ | ABVX – ABIVAX SA | Reduce 28.00% | −129,459 | −0.39 |
| ≡ | MIRM – MIRUM PHARMACEUTICALS INC | Sell | −259,545 | −0.37 |
| ≡ | GRAL – GRAIL INC | Sell | −237,342 | −0.36 |
| ≡ | TENAX THERAPEUTICS INC | Add 230.00% | 1,008,640 | 0.36 |
| ≡ | SION – SIONNA THERAPEUTICS INC | Reduce 44.00% | −520,659 | −0.35 |
| ≡ | SUTRO BIOPHARMA INC | Buy | 715,307 | 0.35 |
| ≡ | ANRO – ALTO NEUROSCIENCE INC | Add 13.00% | 225,500 | 0.32 |
| ≡ | CVS – CVS HEALTH CORP | Sell | −220,000 | −0.31 |
| ≡ | GKOS – GLAUKOS CORP | Sell | −140,000 | −0.28 |
| ≡ | RGEN – REPLIGEN CORP | Reduce 11.00% | −35,000 | −0.28 |
| ≡ | DXCM – DEXCOM INC | Sell | −225,758 | −0.27 |
| ≡ | SAVARA INC | Sell | −2,400,000 | −0.26 |
| ≡ | GH – GUARDANT HEALTH INC | Add 88.00% | 140,000 | 0.25 |
| ≡ | TNGX – TANGO THERAPEUTICS INC | Add 58.00% | 295,118 | 0.25 |
| ≡ | AVR – ANTERIS TECHNOLOGIES GLOBAL | Add 104.00% | 1,750,000 | 0.22 |
| ≡ | SEPN – SEPTERNA INC | Sell | −433,160 | −0.22 |
| ≡ | ADMA – ADMA BIOLOGICS INC | Reduce 47.00% | −416,235 | −0.20 |
| ≡ | EVOMMUNE INC | Buy | 448,350 | 0.20 |
| ≡ | PHATHOM PHARMACEUTICALS INC | Buy | 925,000 | 0.20 |
| ≡ | PALISADE BIO INC | Reduce 26.00% | −3,121,851 | −0.20 |
| ≡ | NMRA – NEUMORA THERAPEUTICS INC. | Buy | 5,104,097 | 0.19 |
| ≡ | ZYME – ZYMEWORKS INC | Add 8.00% | 248,228 | 0.19 |
| ≡ | GOSS – GOSSAMER BIO INC | Sell | −3,139,669 | −0.17 |
| ≡ | MAPLIGHT THERAPEUTICS INC | Sell | −550,000 | −0.17 |
| ≡ | BBNX – BETA BIONICS INC | Add 40.00% | 240,000 | −0.16 |
| ≡ | XENE – XENON PHARMACEUTICALS INC | Sell | −200,791 | −0.16 |
| ≡ | TWST – TWIST BIOSCIENCE CORP | Buy | 150,000 | 0.14 |
| ≡ | KESTRA MED TECHNOLOGIES LTD | Sell | −285,000 | −0.13 |
| ≡ | SURROZEN INC | Buy | 229,393 | 0.13 |
| ≡ | IMVT – IMMUNOVANT INC | Reduce 20.00% | −397,507 | −0.13 |
| ≡ | CAPRICOR THERAPEUTICS INC | Sell | −242,100 | −0.12 |
| ≡ | AGOMAB THERAPEUTICS NV | Buy | 600,000 | 0.12 |
| ≡ | IKT – INHIBIKASE THERAPEUTICS INC | Reduce 57.00% | −3,106,568 | −0.12 |
| ≡ | EOLS – EVOLUS INC | Buy | 1,286,862 | 0.10 |
| ≡ | BHVNCALL – BIOHAVEN LTD | Sell | −500,000 | −0.10 |
| ≡ | KYMR – KYMERA THERAPEUTICS INC | Sell | −69,935 | −0.10 |
| ≡ | PEPG – PEPGEN INC | Sell | −829,870 | −0.10 |
| ≡ | X4 PHARMACEUTICALS INC | Add 7.00% | 423,196 | 0.09 |
| ≡ | TECTONIC THERAPEUTIC INC | Sell | −250,000 | −0.09 |
| ≡ | DRUG – BRIGHT MINDS BIOSCIENCES INC | Reduce 16.00% | −71,746 | −0.09 |
| ≡ | AQST – AQUESTIVE THERAPEUTICS INC | Sell | −747,193 | −0.09 |
| ≡ | OCULCALL – OCULAR THERAPEUTIX INC | Buy | 500,000 | 0.08 |
| ≡ | KRYS – KRYSTAL BIOTECH INC | Sell | −17,500 | −0.08 |
| ≡ | OLMA – OLEMA PHARMACEUTICALS INC | Sell | −165,713 | −0.07 |
| ≡ | SDGR – SCHRODINGER INC | Sell | −202,400 | −0.06 |
| ≡ | APELLIS PHARMACEUTICALS INC | Buy | 80,956 | 0.06 |
| ≡ | EDESA BIOTECH INC | Buy | 563,239 | 0.06 |
| ≡ | ADPT – ADAPTIVE BIOTECHNOLOGIES COR | Buy | 152,500 | 0.04 |
| ≡ | CORT – CORCEPT THERAPEUTICS INC | Buy | 50,000 | 0.04 |
| ≡ | BLLN – BILLIONTOONE INC | Add 26.00% | 19,000 | 0.04 |
| ≡ | IMMIX BIOPHARMA INC | Sell | −338,941 | −0.03 |
| ≡ | LXEO – LEXEO THERAPEUTICS INC | Sell | −139,835 | −0.02 |
| ≡ | CTNM – CONTINEUM THERAPEUTICS INC | Reduce 14.00% | −209,000 | 0.02 |
| ≡ | CBIO – CRESCENT BIOPHARMA INC. | Reduce 54.00% | −246,744 | −0.02 |
| ≡ | LENZ THERAPEUTICS INC | Sell | −50,000 | −0.01 |
| ≡ | BIODESIX | Sell | −108,694 | −0.01 |
| ≡ | CPIX – CUMBERLAND PHARMACEUTICALS I | Reduce 42.00% | −144,109 | −0.01 |
| ≡ | NVNO – ENVVENO MEDICAL CORPORATION | Sell | −1,759,035 | −0.01 |
| ≡ | IRD – OPUS GENETICS INC | Reduce 58.00% | −2,489,158 | 0.01 |
| ≡ | IOVA – IOVANCE BIOTHERAPEUTICS INC | Sell | −152,714 | −0.01 |
| ≡ | EXAGEN INC | Buy | 114,893 | 0.01 |
| ≡ | AXGN – AXOGEN INC | Reduce 11.00% | −86,828 | −0.01 |
| ≡ | PALATIN TECHNOLOGIES INC | Reduce 12.00% | −8,055 | 0.00 |
| Q4 2025filed Feb 17, 2640 new31 added17 reduced15 exited | ||||
| ≡ | PRAX – PRAXIS PRECISION MEDICINES I | Add 28.00% | 431,432 | 8.14 |
| ≡ | ARCELLX INC | Reduce 41.00% | −1,002,282 | −4.02 |
| ≡ | MRUS 10/21/22 P30 – MERUS N V | Sell | −1,353,093 | −3.60 |
| ≡ | INSM – INSMED INC | Sell | −702,130 | −2.86 |
| Q3 2025filed Nov 14, 2521 new28 added13 reduced14 exited | ||||
| ≡ | VERONA PHARMA PLC | Reduce 90.00% | −4,983,503 | −17.25 |
| ≡ | CELC – CELCUITY INC | Add 81.00% | 1,323,111 | 3.34 |
| ≡ | MRUS 10/21/22 P30 – MERUS N V | Add 91.00% | 644,917 | 2.25 |
| ≡ | TVTX – TRAVERE THERAPEUTICS INC | Add 355.00% | 2,960,363 | |
| Q2 2025filed Aug 14, 2524 new7 added27 reduced26 exited | ||||
| ≡ | ASND – ASCENDIS PHARMA A/S | Buy | 963,886 | 6.01 |
| ≡ | AMICUS THERAPEUTICS INC | Reduce 65.00% | −14,051,697 | −4.65 |
| ≡ | VERONA PHARMA PLC | Reduce 16.00% | −1,055,749 | 4.11 |
| ≡ | INTRA-CELLULAR THERAPIES INC | Sell | −786,358 | −3.66 |
| ≡ | ||||
| Q1 2025filed Aug 6, 2519 new12 added27 reduced31 exited | ||||
| ≡ | EWTX – EDGEWISE THERAPEUTICS INC | Add 144.00% | 3,861,791 | 3.14 |
| ≡ | IOVA – IOVANCE BIOTHERAPEUTICS INC | Reduce 43.00% | −9,400,478 | −2.95 |
| ≡ | PCVX – VAXCYTE INC | Reduce 59.00% | −1,011,850 | −2.88 |
| ≡ | NUVALENT INC | Reduce 38.00% | −986,009 | −1.48 |
| Q4 2024filed Feb 14, 2524 new9 added39 reduced33 exited | ||||
| ≡ | SOLENO THERAPEUTICS INC | Reduce 53.00% | −1,703,936 | −1.59 |
| ≡ | BHVN – BIOHAVEN LTD | Sell | −1,485,232 | −1.57 |
| ≡ | APPLIED THERAPEUTICS INC | Reduce 89.00% | −7,145,000 | −1.42 |
| ≡ | PRAX – PRAXIS PRECISION MEDICINES I | Add 14.00% | 165,700 | 1.37 |
| Q3 2024filed Nov 14, 2417 new20 added19 reduced19 exited | ||||
| ≡ | CEREVEL THERAPEUTICS HLDNG I | Sell | −10,794,876 | −10.63 |
| ≡ | VERONA PHARMA PLC | Add 160.00% | 3,882,208 | 3.00 |
| ≡ | NUVALENT INC | Add 17.00% | 430,158 | 1.79 |
| ≡ | MDGL – MADRIGAL PHARMACEUTICALS INC | Sell | −264,600 | −1.79 |
| Q2 2024filed Aug 16, 2422 new17 added29 reduced24 exited | ||||
| ≡ | INHIBRX INC | Sell | −4,256,104 | −2.60 |
| ≡ | FUSION PHARMACEUTICALS INC | Sell | −6,825,395 | −2.55 |
| ≡ | INTRA-CELLULAR THERAPIES INC | Add 63.00% | 661,052 | 1.55 |
| ≡ | IMTX – IMMATICS N.V | Add 76.00% | 3,503,750 | 1.42 |
| ≡ | ||||
| Q1 2024filed Aug 6, 2429 new34 added15 reduced18 exited | ||||
| ≡ | LIANBIO | Sell | −57,558,451 | −5.74 |
| ≡ | IOVA – IOVANCE BIOTHERAPEUTICS INC | Add 61.00% | 7,293,576 | 2.82 |
| ≡ | CYMABAY THERAPEUTICS INC | Sell | −4,024,400 | −2.12 |
| ≡ | FUSION PHARMACEUTICALS INC | Add 148.00% | 4,074,000 | 1.96 |
| Q4 2023filed Feb 26, 2423 new26 added17 reduced19 exited | ||||
| ≡ | CEREVEL THERAPEUTICS HLDNG I | Add 9.00% | 876,808 | 3.03 |
| ≡ | IMVT – IMMUNOVANT INC | Reduce 39.00% | −1,486,609 | −2.70 |
| ≡ | ARGX – ARGENX SE | Sell | −150,600 | −2.47 |
| ≡ | AKERO THERAPEUTICS INC | Reduce 40.00% | −651,650 | −2.23 |
| Q3 2023filed Nov 14, 2317 new21 added23 reduced15 exited | ||||
| ≡ | IMVT – IMMUNOVANT INC | Add 51.00% | 1,290,908 | 3.50 |
| ≡ | SOLENO THERAPEUTICS INC | Add 39.00% | 866,789 | 2.75 |
| ≡ | APELLIS PHARMACEUTICALS INC | Sell | −812,037 | −2.14 |
| ≡ | REATA PHARMACEUTICALS INC | Sell | −670,206 | −1.98 |
| Q2 2023filed Aug 24, 2318 new18 added26 reduced22 exited | ||||
| ≡ | CEREVEL THERAPEUTICS HLDNG I | Add 55.00% | 3,576,658 | 4.59 |
| ≡ | PROMETHEUS BIOSCIENCES INC | Sell | −1,272,694 | −4.03 |
| ≡ | REATA PHARMACEUTICALS INC | Reduce 69.00% | −1,499,070 | −3.85 |
| ≡ | MDGL – MADRIGAL PHARMACEUTICALS INC | Reduce 53.00% | −347,575 | −2.63 |
| ≡ | XBIPUT – SPDR SERIES TRUST | Buy | 1,100,000 | 2.39 |
| ≡ | AMLX – AMYLYX PHARMACEUTICALS INC | Reduce 7.00% | −667,483 | −1.65 |
| ≡ | APGE – APOGEE THERAPEUTICS INC | Add 72.00% | 978,662 | 1.62 |
| ≡ | VERONA PHARMA PLC | Sell | −524,088 | −1.58 |
| ≡ | AKERO THERAPEUTICS INC | Sell | −1,135,766 | −1.52 |
| ≡ | CELC – CELCUITY INC | Add 7.00% | 203,881 | 1.49 |
| ≡ | MEIRAGTX HLDGS PLC | Reduce 18.00% | −2,300,000 | −1.47 |
| ≡ | EXACT SCIENCES CORP | Add 158.00% | 735,000 | 1.45 |
| ≡ | SYRE – SPYRE THERAPEUTICS INC | Add 150.00% | 1,839,780 | 1.21 |
| ≡ | BLTE – BELITE BIO INC | Add 732.00% | 364,451 | 1.08 |
| ≡ | DYN – DYNE THERAPEUTICS INC | Add 544.00% | 2,938,500 | 1.02 |
| ≡ | AORT – ARTIVION INC | Reduce 15.00% | −297,710 | −1.02 |
| ≡ | PEN – PENUMBRA INC | Reduce 50.00% | −110,018 | −0.97 |
| ≡ | IVVD – INVIVYD INC | Buy | 21,785,166 | 0.96 |
| ≡ | NBIX – NEUROCRINE BIOSCIENCES INC | Reduce 26.00% | −119,000 | −0.95 |
| ≡ | NRIX – NURIX THERAPEUTICS INC | Add 151.00% | 2,139,728 | 0.83 |
| ≡ | NUVALENT INC | Add 7.00% | 102,769 | −0.83 |
| ≡ | CENTESSA PHARMACEUTICALS PLC | Reduce 6.00% | −183,268 | −0.82 |
| ≡ | DHR – DANAHER CORPORATION | Buy | 200,000 | 0.82 |
| ≡ | BSX – BOSTON SCIENTIFIC CORP | Add 216.00% | 669,000 | 0.81 |
| ≡ | VRDN – VIRIDIAN THERAPEUTICS INC | Add 108.00% | 1,580,303 | 0.80 |
| ≡ | INBX – INHIBRX BIOSCIENCES INC | Add 9.00% | 125,000 | 0.78 |
| ≡ | CIDARA THERAPEUTICS INC | Buy | 165,131 | 0.65 |
| ≡ | IRON – DISC MEDICINE INC | Buy | 450,743 | 0.64 |
| ≡ | ANRO – ALTO NEUROSCIENCE INC | Add 1049.00% | 1,629,027 | 0.55 |
| ≡ | ENGN – ENGENE HOLDINGS INC | Add 180.00% | 3,771,840 | 0.54 |
| ≡ | ZYME – ZYMEWORKS INC | Add 56.00% | 1,171,187 | 0.52 |
| ≡ | JAZZ – JAZZ PHARMACEUTICALS PLC | Buy | 170,000 | 0.52 |
| ≡ | AQST – AQUESTIVE THERAPEUTICS INC | Reduce 80.00% | −3,012,906 | −0.51 |
| ≡ | PALISADE BIO INC | Buy | 12,050,000 | 0.50 |
| ≡ | AXGN – AXOGEN INC | Buy | 784,140 | 0.46 |
| ≡ | X4 PHARMACEUTICALS INC | Buy | 6,314,452 | 0.45 |
| ≡ | BCRX – BIOCRYST PHARMACEUTICALS INC | Buy | 3,162,529 | 0.44 |
| ≡ | BIIB – BIOGEN INC | Buy | 124,000 | 0.39 |
| ≡ | ALDX – ALDEYRA THERAPEUTICS INC | Reduce 20.00% | −1,036,679 | −0.38 |
| ≡ | MIRM – MIRUM PHARMACEUTICALS INC | Buy | 259,545 | 0.37 |
| ≡ | RAPT THERAPEUTICS INC | Add 349.00% | 642,000 | 0.36 |
| ≡ | GRAL – GRAIL INC | Buy | 237,342 | 0.36 |
| ≡ | TVTX – TRAVERE THERAPEUTICS INC | Add 13.00% | 483,565 | 0.35 |
| ≡ | IMTX – IMMATICS N.V | Add 11.00% | 1,000,000 | −0.31 |
| ≡ | CVS – CVS HEALTH CORP | Buy | 220,000 | 0.31 |
| ≡ | GH – GUARDANT HEALTH INC | Buy | 160,000 | 0.29 |
| ≡ | RLAY – RELAY THERAPEUTICS INC | Buy | 1,903,245 | 0.29 |
| ≡ | GKOS – GLAUKOS CORP | Buy | 140,000 | 0.28 |
| ≡ | DXCM – DEXCOM INC | Buy | 225,758 | 0.27 |
| ≡ | SAVARA INC | Buy | 2,400,000 | 0.26 |
| ≡ | IRTC – IRHYTHM TECHNOLOGIES INC | Reduce 12.00% | −15,000 | −0.26 |
| ≡ | EWTX – EDGEWISE THERAPEUTICS | Add 17.00% | 662,080 | 0.23 |
| ≡ | ISRG – INTUITIVE SURGICAL INC | Add 69.00% | 35,800 | 0.23 |
| ≡ | CRVS – CORVUS PHARMACEUTICALS INC | Reduce 52.00% | −746,154 | −0.20 |
| ≡ | PALVELLA THERAPEUTICS INC NE | Reduce 33.00% | −128,806 | −0.20 |
| ≡ | JANX – JANUX THERAPEUTICS INC | Sell | −292,686 | −0.20 |
| ≡ | TEM – TEMPUS AI INC | Sell | −85,000 | −0.19 |
| ≡ | ADMA – ADMA BIOLOGICS INC | Reduce 23.00% | −270,000 | −0.19 |
| ≡ | LONA – ATHIRA PHARMA INC | Add 244.00% | 1,319,026 | 0.19 |
| ≡ | IMVT – IMMUNOVANT INC | Add 26.00% | 407,000 | 0.18 |
| ≡ | OCS – OCULIS HOLDING AG | Buy | 493,827 | 0.18 |
| ≡ | KYMR – KYMERA THERAPEUTICS INC | Reduce 59.00% | −99,861 | −0.17 |
| ≡ | MAPLIGHT THERAPEUTICS INC | Buy | 550,000 | 0.17 |
| ≡ | BBNX – BETA BIONICS INC | Add 117.00% | 325,000 | 0.17 |
| ≡ | ABVX – ABIVAX SA | Add 18.00% | 69,735 | 0.17 |
| ≡ | PTGX – PROTAGONIST THERAPEUTICS INC | Add 31.00% | 320,291 | 0.17 |
| ≡ | HTFL – HEARTFLOW INC | Sell | −150,000 | −0.14 |
| ≡ | KESTRA MED TECHNOLOGIES LTD | Buy | 285,000 | 0.13 |
| ≡ | KOD – KODIAK SCIENCES INC | Add 34.00% | 214,323 | 0.13 |
| ≡ | CAPRICOR THERAPEUTICS INC | Buy | 242,100 | 0.12 |
| ≡ | GOSS – GOSSAMER BIO INC | Reduce 18.00% | −673,128 | −0.11 |
| ≡ | ORKA – ORUKA THERAPEUTICS INC | Add 16.00% | 208,480 | 0.11 |
| ≡ | BLLN – BILLIONTOONE INC | Buy | 72,812 | 0.11 |
| ≡ | BHVNCALL – BIOHAVEN LTD | Buy | 500,000 | 0.10 |
| ≡ | RGEN – REPLIGEN CORP | Add 17.00% | 45,113 | −0.10 |
| ≡ | KRYS – KRYSTAL BIOTECH INC | Reduce 50.00% | −17,500 | −0.10 |
| ≡ | TENAX THERAPEUTICS INC | Buy | 439,142 | 0.10 |
| ≡ | SCPHARMACEUTICALS INC | Sell | −583,142 | −0.09 |
| ≡ | TECTONIC THERAPEUTIC INC | Buy | 250,000 | 0.09 |
| ≡ | TNGX – TANGO THERAPEUTICS INC | Buy | 513,035 | 0.08 |
| ≡ | VKTX – VIKING THERAPEUTICS INC | Sell | −105,597 | −0.08 |
| ≡ | COGT – COGENT BIOSCIENCES INC | Buy | 121,082 | 0.08 |
| ≡ | PYXS – PYXIS ONCOLOGY INC | Sell | −1,178,307 | −0.07 |
| ≡ | OLMA – OLEMA PHARMACEUTICALS INC | Buy | 165,713 | 0.07 |
| ≡ | SEPN – SEPTERNA INC | Reduce 20.00% | −108,290 | −0.07 |
| ≡ | SDGR – SCHRODINGER INC | Buy | 202,400 | 0.06 |
| ≡ | CTNM – CONTINEUM THERAPEUTICS INC | Add 105.00% | 750,000 | 0.06 |
| ≡ | ROIV – ROIVANT SCIENCES LTD | Add 8.00% | 617,000 | −0.06 |
| ≡ | SPRYPUT – ARS PHARMACEUTICALS INC | Sell | −200,000 | −0.06 |
| ≡ | SAB BIOTHERAPEUTICS INC | Buy | 803,210 | 0.05 |
| ≡ | TRIB – TRINITY BIOTECH PLC | Sell | −1,790,000 | −0.05 |
| ≡ | LYRA THERAPEUTICS INC | Sell | −229,382 | −0.04 |
| ≡ | CONNECT BIOPHARMA HLDGS LTD | Buy | 792,696 | 0.04 |
| ≡ | QURE – UNIQURE NV | Sell | −20,000 | −0.03 |
| ≡ | IMMIX BIOPHARMA INC | Buy | 338,941 | 0.03 |
| ≡ | RAPP – RAPPORT THERAPEUTICS INC | Add 67.00% | 270,000 | 0.03 |
| ≡ | CPIX – CUMBERLAND PHARMACEUTICALS I | Buy | 341,087 | 0.02 |
| ≡ | MDLN – MEDLINE INC | Buy | 28,000 | 0.02 |
| ≡ | PALATIN TECHNOLOGIES INC | Buy | 70,000 | 0.02 |
| ≡ | LENZ THERAPEUTICS INC | Buy | 50,000 | 0.01 |
| ≡ | APYX – APYX MEDICAL CORPORATION | Sell | −150,000 | −0.01 |
| ≡ | IOVA – IOVANCE BIOTHERAPEUTICS INC | Buy | 152,714 | 0.01 |
| ≡ | CELC 2.75 08/01/31 – CELCUITY INC | Buy | 6,500,000 | 0.00 |
| 2.11 |
| ≡ | ROIV – ROIVANT SCIENCES LTD | Add 121.00% | 4,036,996 | 1.79 |
| ≡ | AMLX – AMYLYX PHARMACEUTICALS INC | Add 13.00% | 1,050,000 | 1.60 |
| ≡ | CENTESSA PHARMACEUTICALS PLC | Add 170.00% | 1,953,967 | 1.58 |
| ≡ | SOLENO THERAPEUTICS INC | Sell | −430,439 | −1.30 |
| ≡ | PEN – PENUMBRA INC | Add 572.00% | 187,750 | 1.27 |
| ≡ | PRAX – PRAXIS PRECISION MEDICINES I | Add 108.00% | 811,633 | 1.20 |
| ≡ | ABVX – ABIVAX SA | Buy | 388,608 | 0.93 |
| ≡ | XBIPUT – SPDR SERIES TRUST | Sell | −300,000 | −0.90 |
| ≡ | EOLS – EVOLUS INC | Sell | −2,474,843 | −0.82 |
| ≡ | INBX – INHIBRX BIOSCIENCES INC | Add 36.00% | 349,815 | 0.76 |
| ≡ | AORT – ARTIVION INC | Reduce 28.00% | −773,703 | −0.73 |
| ≡ | EXACT SCIENCES CORP | Buy | 465,487 | 0.72 |
| ≡ | PALVELLA THERAPEUTICS INC NE | Buy | 395,093 | 0.70 |
| ≡ | ORKA – ORUKA THERAPEUTICS INC | Buy | 1,268,021 | 0.69 |
| ≡ | PODD – INSULET CORP | Sell | −60,387 | −0.69 |
| ≡ | BBNX – BETA BIONICS INC | Reduce 83.00% | −1,315,664 | −0.68 |
| ≡ | VRDN – VIRIDIAN THERAPEUTICS INC | Add 227.00% | 1,014,893 | 0.67 |
| ≡ | NBIX – NEUROCRINE BIOSCIENCES INC | Add 76.00% | 195,000 | 0.63 |
| ≡ | IRTC – IRHYTHM TECHNOLOGIES INC | Buy | 123,000 | 0.60 |
| ≡ | DYN – DYNE THERAPEUTICS INC | Reduce 76.00% | −1,706,946 | −0.58 |
| ≡ | CRL – CHARLES RIV LABS INTL INC | Sell | −100,000 | −0.55 |
| ≡ | IMVT – IMMUNOVANT INC | Reduce 26.00% | −550,000 | −0.51 |
| ≡ | INSM – INSMED INC | Add 8.00% | 51,878 | 0.49 |
| ≡ | EWTX – EDGEWISE THERAPEUTICS INC | Reduce 18.00% | −844,055 | −0.46 |
| ≡ | ZYME – ZYMEWORKS INC | Add 64.00% | 815,389 | 0.43 |
| ≡ | ENGN – ENGENE HOLDINGS INC | Buy | 2,097,236 | 0.40 |
| ≡ | ADMA – ADMA BIOLOGICS INC | Reduce 12.00% | −150,000 | −0.38 |
| ≡ | DRUG – BRIGHT MINDS BIOSCIENCES INC | Add 7.00% | 28,600 | 0.37 |
| ≡ | RARE – ULTRAGENYX PHARMACEUTICAL IN | Sell | −270,000 | −0.35 |
| ≡ | APGE – APOGEE THERAPEUTICS INC | Add 14.00% | 169,841 | −0.34 |
| ≡ | RAPP – RAPPORT THERAPEUTICS INC | Buy | 403,923 | 0.34 |
| ≡ | AQST – AQUESTIVE THERAPEUTICS INC | Add 72.00% | 1,569,679 | 0.33 |
| ≡ | CTMX – CYTOMX THERAPEUTICS INC | Add 38.00% | 2,686,539 | 0.30 |
| ≡ | KOD – KODIAK SCIENCES INC | Buy | 634,577 | 0.29 |
| ≡ | VKTX – VIKING THERAPEUTICS INC | Reduce 72.00% | −275,103 | −0.29 |
| ≡ | GOSS – GOSSAMER BIO INC | Buy | 3,812,797 | 0.28 |
| ≡ | RGEN – REPLIGEN CORP | Add 63.00% | 104,428 | 0.27 |
| ≡ | CELC 2.75 08/01/31 – CELCUITY INC | Buy | 0 | 0.25 |
| ≡ | SYRE – SPYRE THERAPEUTICS INC | Reduce 20.00% | −300,000 | −0.25 |
| ≡ | AKERO THERAPEUTICS INC | Add 24.00% | 219,879 | −0.24 |
| ≡ | AXSM – AXSOME THERAPEUTICS INC | Reduce 25.00% | −49,634 | −0.24 |
| ≡ | CAPRICOR THERAPEUTICS INC | Sell | −650,000 | −0.23 |
| ≡ | BSX – BOSTON SCIENTIFIC CORP | Add 11.00% | 30,000 | −0.23 |
| ≡ | ISRG – INTUITIVE SURGICAL INC | Add 16.00% | 7,000 | −0.23 |
| ≡ | ALDX – ALDEYRA THERAPEUTICS INC | Add 29.00% | 1,170,680 | 0.21 |
| ≡ | TEM – TEMPUS AI INC | Buy | 85,000 | 0.19 |
| ≡ | GMED – GLOBUS MED INC | Sell | −88,500 | −0.19 |
| ≡ | KRYS – KRYSTAL BIOTECH INC | Buy | 35,000 | 0.17 |
| ≡ | BBOT – HELIX ACQUISITION CORP II | Sell | −398,000 | −0.15 |
| ≡ | HTFL – HEARTFLOW INC | Buy | 150,000 | 0.14 |
| ≡ | NVNO – ENVVENO MEDICAL CORPORATION | Add 37.00% | 474,069 | −0.14 |
| ≡ | AMICUS THERAPEUTICS INC | Reduce 14.00% | −1,041,979 | −0.12 |
| ≡ | PEPG – PEPGEN INC | Buy | 829,870 | 0.11 |
| ≡ | BLTE – BELITE BIO INC | Buy | 49,788 | 0.10 |
| ≡ | ASND – ASCENDIS PHARMA A/S | Add 13.00% | 124,615 | 0.10 |
| ≡ | NRIX – NURIX THERAPEUTICS INC | Add 29.00% | 319,164 | −0.08 |
| ≡ | OBIO – ORCHESTRA BIOMED HLDGS INC | Add 15.00% | 700,000 | −0.07 |
| ≡ | PYXS – PYXIS ONCOLOGY INC | Buy | 1,178,307 | 0.07 |
| ≡ | LONA – ATHIRA PHARMA INC | Buy | 540,296 | 0.06 |
| ≡ | KYMR – KYMERA THERAPEUTICS INC | Reduce 19.00% | −40,310 | −0.06 |
| ≡ | ATHA 04/16/21 P15 – ATHIRA PHARMA INC | Sell | −5,402,964 | −0.06 |
| ≡ | SPRYPUT – ARS PHARMACEUTICALS INC | Buy | 200,000 | 0.06 |
| ≡ | LYRA THERAPEUTICS INC | Reduce 10.00% | −25,768 | −0.04 |
| ≡ | CAPRICOR THERAPEUTICS INC | Sell | −100,000 | −0.04 |
| ≡ | QURE – UNIQURE NV | Buy | 20,000 | 0.03 |
| ≡ | FBRX – FORTE BIOSCIENCES INC | Sell | −68,192 | −0.03 |
| ≡ | SCPHARMACEUTICALS INC | Add 17.00% | 83,142 | 0.02 |
| ≡ | BIODESIX | Buy | 108,694 | 0.02 |
| ≡ | NUVALENT INC | Add 14.00% | 187,156 | 0.02 |
| ≡ | BDSX – BIODESIX INC | Sell | −2,173,880 | −0.02 |
| ≡ | ANRO – ALTO NEUROSCIENCE INC | Buy | 155,366 | 0.02 |
| ≡ | KALA BIO INC | Sell | −55,227 | −0.01 |
| EWTX – EDGEWISE THERAPEUTICS INC |
| Reduce 29.00% |
| −1,907,379 |
| −2.89 |
| ≡ | SOLENO THERAPEUTICS INC | Reduce 71.00% | −1,076,163 | −2.50 |
| ≡ | OMDA – OMADA HEALTH INC | Buy | 2,426,330 | 1.61 |
| ≡ | IOVA – IOVANCE BIOTHERAPEUTICS INC | Sell | −12,711,788 | −1.50 |
| ≡ | ROIV – ROIVANT SCIENCES LTD | Buy | 3,331,465 | 1.36 |
| ≡ | MRUS 10/21/22 P30 – MERUS N V | Buy | 708,176 | 1.35 |
| ≡ | ALDX – ALDEYRA THERAPEUTICS INC | Reduce 56.00% | −5,224,220 | −1.32 |
| ≡ | ARGX – ARGENX SE | Sell | −59,510 | −1.24 |
| ≡ | CAI – CARIS LIFE SCIENCES INC | Buy | 1,098,163 | 1.06 |
| ≡ | MERUS N V | Sell | −690,485 | −1.03 |
| ≡ | CENTESSA PHARMACEUTICALS PLC | Reduce 62.00% | −1,893,460 | −1.00 |
| ≡ | INSM – INSMED INC | Add 28.00% | 140,952 | 0.99 |
| ≡ | PCVX – VAXCYTE INC | Sell | −706,567 | −0.94 |
| ≡ | EOLS – EVOLUS INC | Reduce 40.00% | −1,654,299 | −0.93 |
| ≡ | XBIPUT – SPDR SERIES TRUST | Buy | 300,000 | 0.90 |
| ≡ | ARCELLX INC | Reduce 15.00% | −448,478 | −0.88 |
| ≡ | NBIX – NEUROCRINE BIOSCIENCES INC | Add 155.00% | 155,000 | 0.77 |
| ≡ | AXSM – AXSOME THERAPEUTICS INC | Reduce 44.00% | −156,573 | −0.71 |
| ≡ | JANX – JANUX THERAPEUTICS INC | Reduce 70.00% | −677,726 | −0.68 |
| ≡ | AKERO THERAPEUTICS INC | Add 16.00% | 122,927 | 0.63 |
| ≡ | BSX – BOSTON SCIENTIFIC CORP | Add 115.00% | 150,000 | 0.62 |
| ≡ | CTMX – CYTOMX THERAPEUTICS INC | Buy | 6,993,646 | 0.57 |
| ≡ | CRL – CHARLES RIV LABS INTL INC | Buy | 100,000 | 0.55 |
| ≡ | MDGL – MADRIGAL PHARMACEUTICALS INC | Sell | −46,500 | −0.54 |
| ≡ | SYRE – SPYRE THERAPEUTICS INC | Reduce 34.00% | −783,827 | −0.49 |
| ≡ | IMVT – IMMUNOVANT INC | Reduce 25.00% | −706,182 | −0.48 |
| ≡ | TVTX – TRAVERE THERAPEUTICS INC | Buy | 834,252 | 0.45 |
| ≡ | DXCM – DEXCOM INC | Sell | −178,000 | −0.43 |
| ≡ | EWTXCALL – EDGEWISE THERAPEUTICS INC | Sell | −500,000 | −0.39 |
| ≡ | ACRV – ACRIVON THERAPEUTICS INC | Sell | −5,360,858 | −0.38 |
| ≡ | RARE – ULTRAGENYX PHARMACEUTICAL IN | Buy | 270,000 | 0.35 |
| ≡ | CARGO THERAPEUTICS INC | Sell | −2,431,085 | −0.35 |
| ≡ | KYMR – KYMERA THERAPEUTICS INC | Buy | 210,106 | 0.33 |
| ≡ | NRIX – NURIX THERAPEUTICS INC | Add 269.00% | 799,432 | 0.33 |
| ≡ | PEN – PENUMBRA INC | Buy | 32,797 | 0.30 |
| ≡ | NUVALENT INC | Reduce 16.00% | −258,788 | −0.30 |
| ≡ | EYPT – EYEPOINT PHARMACEUTICALS INC | Sell | −1,537,274 | −0.29 |
| ≡ | CBIO – CRESCENT BIOPHARMA INC. | Buy | 453,686 | 0.26 |
| ≡ | IRON – DISC MEDICINE INC | Sell | −150,000 | −0.26 |
| ≡ | CTNM – CONTINEUM THERAPEUTICS INC | Reduce 51.00% | −741,763 | −0.25 |
| ≡ | ADPT – ADAPTIVE BIOTECHNOLOGIES COR | Sell | −930,972 | −0.24 |
| ≡ | OCUL – OCULAR THERAPEUTIX INC | Sell | −915,775 | −0.24 |
| ≡ | CAPRICOR THERAPEUTICS INC | Buy | 650,000 | 0.23 |
| ≡ | CRVS – CORVUS PHARMACEUTICALS INC | Buy | 1,438,595 | 0.21 |
| ≡ | DELCATH SYS INC | Sell | −462,422 | −0.21 |
| ≡ | SEPN – SEPTERNA INC | Buy | 541,450 | 0.21 |
| ≡ | ZYME – ZYMEWORKS INC | Reduce 32.00% | −589,398 | −0.21 |
| ≡ | RAPT THERAPEUTICS INC | Sell | −4,418,947 | −0.19 |
| ≡ | GMED – GLOBUS MED INC | Buy | 88,500 | 0.19 |
| ≡ | NVNO – ENVVENO MEDICAL CORPORATION | Buy | 1,284,966 | 0.19 |
| ≡ | KESTRA MED TECHNOLOGIES LTD | Sell | −200,000 | −0.18 |
| ≡ | ISRG – INTUITIVE SURGICAL INC | Add 11.00% | 4,500 | 0.18 |
| ≡ | PRAX – PRAXIS PRECISION MEDICINES I | Reduce 23.00% | −227,973 | −0.17 |
| ≡ | RGEN – REPLIGEN CORP | Add 28.00% | 36,199 | 0.16 |
| ≡ | XENE – XENON PHARMACEUTICALS INC | Reduce 38.00% | −124,533 | −0.16 |
| ≡ | ONKURE THERAPEUTICS INC | Sell | −1,004,439 | −0.15 |
| ≡ | AVTX – AVALO THERAPEUTICS INC | Reduce 73.00% | −380,333 | −0.12 |
| ≡ | AQST – AQUESTIVE THERAPEUTICS INC | Reduce 41.00% | −1,536,788 | −0.12 |
| ≡ | VRDN – VIRIDIAN THERAPEUTICS INC | Reduce 32.00% | −212,155 | −0.09 |
| ≡ | LYRA THERAPEUTICS INC | Buy | 255,150 | 0.08 |
| ≡ | IKT – INHIBIKASE THERAPEUTICS INC | Reduce 8.00% | −492,707 | −0.08 |
| ≡ | MREO – MEREO BIOPHARMA GROUP PLC | Sell | −876,961 | −0.07 |
| ≡ | VKTX – VIKING THERAPEUTICS INC | Reduce 25.00% | −128,305 | −0.07 |
| ≡ | ATHA 04/16/21 P15 – ATHIRA PHARMA INC | Buy | 5,402,964 | 0.06 |
| ≡ | LYRA – LYRA THERAPEUTICS INC | Sell | −12,757,562 | −0.06 |
| ≡ | CELC – CELCUITY INC | Reduce 31.00% | −729,071 | −0.06 |
| ≡ | ATHIRA PHARMA INC | Sell | −5,402,964 | −0.05 |
| ≡ | RAPT THERAPEUTICS INC | Buy | 183,890 | 0.05 |
| ≡ | KALA BIO INC | Reduce 80.00% | −222,383 | −0.05 |
| ≡ | TRIB – TRINITY BIOTECH PLC | Buy | 1,790,000 | 0.04 |
| ≡ | AVR – ANTERIS TECHNOLOGIES GLOBAL | Reduce 20.00% | −434,870 | −0.04 |
| ≡ | CAPRICOR THERAPEUTICS INC | Buy | 100,000 | 0.04 |
| ≡ | TRAWS PHARMA INC | Sell | −421,781 | −0.03 |
| ≡ | RCKT – ROCKET PHARMACEUTICALS INC | Sell | −140,726 | −0.03 |
| ≡ | FBRX – FORTE BIOSCIENCES INC | Buy | 68,192 | 0.03 |
| ≡ | PODD – INSULET CORP | Reduce 16.00% | −11,210 | 0.02 |
| ≡ | CGEM – CULLINAN THERAPEUTICS INC | Sell | −80,100 | −0.02 |
| ≡ | INBX – INHIBRX BIOSCIENCES INC | Reduce 8.00% | −86,134 | −0.02 |
| ≡ | APPLIED THERAPEUTICS INC | Sell | −860,000 | −0.01 |
| ≡ | NBTX – NANOBIOTIX | Sell | −105,053 | −0.01 |
| ≡ | PRAX – PRAXIS PRECISION MEDICINES I | Reduce 26.00% | −348,841 | −1.47 |
| ≡ | CENTESSA PHARMACEUTICALS PLC | Reduce 52.00% | −3,308,825 | −1.35 |
| ≡ | INSM – INSMED INC | Add 254.00% | 365,300 | 1.10 |
| ≡ | CARGO THERAPEUTICS INC | Reduce 34.00% | −1,251,919 | −1.09 |
| ≡ | PRAXCALL – PRAXIS PRECISION MEDICINES I | Sell | −500,000 | −1.05 |
| ≡ | MERUS N V | Buy | 690,485 | 1.03 |
| ≡ | PODD – INSULET CORP | Reduce 69.00% | −160,672 | −0.98 |
| ≡ | RYTM – RHYTHM PHARMACEUTICALS INC | Reduce 31.00% | −1,132,028 | −0.83 |
| ≡ | SLDB – SOLID BIOSCIENCES INC | Add 72.00% | 5,000,000 | 0.81 |
| ≡ | INTRA-CELLULAR THERAPIES INC | Reduce 39.00% | −501,970 | 0.74 |
| ≡ | BBNX – BETA BIONICS INC | Buy | 1,593,608 | 0.69 |
| ≡ | VKTX – VIKING THERAPEUTICS INC | Reduce 49.00% | −486,889 | −0.66 |
| ≡ | PRCT – PROCEPT BIOROBOTICS CORP | Sell | −290,659 | −0.64 |
| ≡ | RGEN – REPLIGEN CORP | Buy | 129,801 | 0.58 |
| ≡ | ADMA – ADMA BIOLOGICS INC | Add 54.00% | 482,953 | 0.55 |
| ≡ | MDGL – MADRIGAL PHARMACEUTICALS INC | Buy | 46,500 | 0.54 |
| ≡ | NTRA – NATERA INC | Sell | −125,000 | −0.54 |
| ≡ | PTGX – PROTAGONIST THERAPEUTICS INC | Reduce 14.00% | −180,391 | 0.53 |
| ≡ | DYN – DYNE THERAPEUTICS INC | Add 326.00% | 1,770,126 | 0.51 |
| ≡ | PEN – PENUMBRA INC | Sell | −73,338 | −0.47 |
| ≡ | ARCELLX INC | Reduce 16.00% | −552,410 | −0.47 |
| ≡ | SEPN – SEPTERNA INC | Sell | −750,000 | −0.47 |
| ≡ | BSX – BOSTON SCIENTIFIC CORP | Buy | 130,000 | 0.46 |
| ≡ | SION – SIONNA THERAPEUTICS INC | Buy | 1,251,101 | 0.46 |
| ≡ | VRDN – VIRIDIAN THERAPEUTICS INC | Reduce 56.00% | −826,846 | −0.46 |
| ≡ | ORKA – ORUKA THERAPEUTICS INC | Sell | −845,567 | −0.45 |
| ≡ | DXCM – DEXCOM INC | Buy | 178,000 | 0.43 |
| ≡ | EWTXCALL – EDGEWISE THERAPEUTICS INC | Buy | 500,000 | 0.39 |
| ≡ | ARVN – ARVINAS INC | Sell | −740,749 | −0.39 |
| ≡ | AQST – AQUESTIVE THERAPEUTICS INC | Buy | 3,727,208 | 0.38 |
| ≡ | MRUS 10/21/22 P30 – MERUS N V | Sell | −300,000 | −0.34 |
| ≡ | CGON – CG ONCOLOGY INC | Sell | −419,450 | −0.33 |
| ≡ | OM – OUTSET MED INC | Buy | 833,333 | 0.33 |
| ≡ | SYRE – SPYRE THERAPEUTICS INC | Reduce 10.00% | −261,451 | −0.31 |
| ≡ | EW – EDWARDS LIFESCIENCES CORP | Sell | −145,000 | −0.29 |
| ≡ | AMLX – AMYLYX PHARMACEUTICALS INC | Add 16.00% | 1,100,000 | 0.29 |
| ≡ | TARS – TARSUS PHARMACEUTICALS INC | Sell | −186,662 | −0.28 |
| ≡ | IMVT – IMMUNOVANT INC | Add 33.00% | 704,873 | 0.28 |
| ≡ | JANX – JANUX THERAPEUTICS INC | Add 19.00% | 152,517 | −0.27 |
| ≡ | IRON – DISC MEDICINE INC | Buy | 150,000 | 0.26 |
| ≡ | CRNX – CRINETICS PHARMACEUTICALS IN | Sell | −184,525 | −0.26 |
| ≡ | RAPT 05/21/21 C35 – RAPT THERAPEUTICS INC | Sell | −5,880,000 | −0.25 |
| ≡ | INARI MED INC | Sell | −178,797 | −0.25 |
| ≡ | ADPT – ADAPTIVE BIOTECHNOLOGIES COR | Buy | 930,972 | 0.24 |
| ≡ | AKERO THERAPEUTICS INC | Reduce 33.00% | −392,632 | 0.24 |
| ≡ | EOLS – EVOLUS INC | Reduce 20.00% | −1,016,704 | 0.21 |
| ≡ | APGE – APOGEE THERAPEUTICS INC | Add 7.00% | 75,535 | 0.19 |
| ≡ | DELCATH SYS INC | Add 825.00% | 412,422 | 0.19 |
| ≡ | RAPT THERAPEUTICS INC | Buy | 4,418,947 | 0.19 |
| ≡ | ISRG – INTUITIVE SURGICAL INC | Reduce 36.00% | −22,500 | −0.19 |
| ≡ | KESTRA MED TECHNOLOGIES LTD | Buy | 200,000 | 0.18 |
| ≡ | DRUG – BRIGHT MINDS BIOSCIENCES INC | Add 10.00% | 41,000 | 0.17 |
| ≡ | ZENAS BIOPHARMA INC | Sell | −744,035 | −0.17 |
| ≡ | IRTC – IRHYTHM TECHNOLOGIES INC | Sell | −65,153 | −0.16 |
| ≡ | RAPP – RAPPORT THERAPEUTICS INC | Sell | −311,551 | −0.15 |
| ≡ | IRD – OPUS GENETICS INC | Buy | 4,325,000 | 0.15 |
| ≡ | AVTX – AVALO THERAPEUTICS INC | Buy | 520,000 | 0.15 |
| ≡ | CERIBELL INC | Sell | −180,546 | −0.13 |
| ≡ | ARGX – ARGENX SE | Reduce 12.00% | −7,961 | 0.12 |
| ≡ | VERU – VERU INC | Sell | −6,483,157 | −0.11 |
| ≡ | PERSPECTIVE THERAPEUTICS INC | Sell | −1,190,263 | −0.10 |
| ≡ | LINEAGE CELL THERAPEUTICS IN | Sell | −7,236,843 | −0.10 |
| ≡ | RCKT – ROCKET PHARMACEUTICALS INC | Reduce 63.00% | −237,858 | −0.10 |
| ≡ | ATHA 04/16/21 P15 – ATHIRA PHARMA INC | Sell | −5,402,964 | −0.09 |
| ≡ | PEPG – PEPGEN INC | Sell | −829,536 | −0.09 |
| ≡ | IMMUNITYBIO INC | Sell | −1,221,734 | −0.09 |
| ≡ | BCYC – BICYCLE THERAPEUTICS PLC | Sell | −197,108 | −0.08 |
| ≡ | AXSM – AXSOME THERAPEUTICS INC | Reduce 47.00% | −308,967 | −0.06 |
| ≡ | ZYME – ZYMEWORKS INC | Reduce 12.00% | −265,348 | −0.06 |
| ≡ | VRCA – VERRICA PHARMACEUTICALS INC | Sell | −3,249,669 | −0.06 |
| ≡ | FBRX – FORTE BIOSCIENCES INC | Sell | −95,742 | −0.06 |
| ≡ | KALA BIO INC | Buy | 277,610 | 0.06 |
| ≡ | ATHIRA PHARMA INC | Buy | 5,402,964 | 0.05 |
| ≡ | NRIX – NURIX THERAPEUTICS INC | Reduce 10.00% | −33,061 | −0.04 |
| ≡ | TRIB – TRINITY BIOTECH PLC | Sell | −1,790,000 | −0.04 |
| ≡ | MREO – MEREO BIOPHARMA GROUP PLC | Reduce 19.00% | −208,551 | −0.03 |
| ≡ | FULC – FULCRUM THERAPEUTICS INC | Sell | −238,000 | −0.03 |
| ≡ | AMICUS THERAPEUTICS INC | Reduce 11.00% | −2,781,425 | −0.02 |
| ≡ | NVAXPUT – NOVAVAX INC | Sell | −100,000 | −0.02 |
| ≡ | CGEM – CULLINAN THERAPEUTICS INC | Buy | 80,100 | 0.02 |
| ≡ | BBOT – HELIX ACQUISITION CORP II | Reduce 20.00% | −102,000 | 0.02 |
| ≡ | OCUL – OCULAR THERAPEUTIX INC | Reduce 15.00% | −162,720 | −0.01 |
| ≡ | PYXS – PYXIS ONCOLOGY INC | Sell | −188,462 | −0.01 |
| ≡ | NBTX – NANOBIOTIX | Reduce 61.00% | −161,040 | −0.01 |
| ≡ | TRAWS PHARMA INC | Add 157.00% | 257,624 | −0.01 |
| ≡ |
| APGE – APOGEE THERAPEUTICS INC |
| Reduce 48.00% |
| −967,775 |
| −1.21 |
| ≡ | JANX – JANUX THERAPEUTICS INC | Buy | 817,895 | 1.19 |
| ≡ | VKTX – VIKING THERAPEUTICS INC | Reduce 41.00% | −704,093 | −1.19 |
| ≡ | PCVX – VAXCYTE INC | Reduce 15.00% | −309,191 | −1.07 |
| ≡ | PRAXCALL – PRAXIS PRECISION MEDICINES I | Buy | 500,000 | 1.05 |
| ≡ | PODD – INSULET CORP | Add 63.00% | 90,000 | 0.95 |
| ≡ | NUVALENT INC | Reduce 12.00% | −359,258 | −0.87 |
| ≡ | XBIPUT – SPDR SER TR | Sell | −400,000 | −0.84 |
| ≡ | IOVA – IOVANCE BIOTHERAPEUTICS INC | Reduce 17.00% | −4,505,443 | −0.84 |
| ≡ | EWTX – EDGEWISE THERAPEUTICS INC | Add 15.00% | 355,243 | 0.63 |
| ≡ | TARS – TARSUS PHARMACEUTICALS INC | Reduce 86.00% | −1,109,754 | −0.62 |
| ≡ | VRDN – VIRIDIAN THERAPEUTICS INC | Reduce 47.00% | −1,326,157 | −0.58 |
| ≡ | AMLX – AMYLYX PHARMACEUTICALS INC | Add 219.00% | 4,648,699 | 0.55 |
| ≡ | CRNX – CRINETICS PHARMACEUTICALS IN | Reduce 75.00% | −540,173 | −0.53 |
| ≡ | IKT – INHIBIKASE THERAPEUTICS INC | Buy | 5,925,000 | 0.52 |
| ≡ | INSTIL BIO INC | Sell | −345,545 | −0.49 |
| ≡ | LIVN – LIVANOVA PLC | Sell | −429,000 | −0.48 |
| ≡ | PEN – PENUMBRA INC | Buy | 73,338 | 0.47 |
| ≡ | SPRINGWORKS THERAPEUTICS INC | Sell | −692,263 | −0.47 |
| ≡ | MDT – MEDTRONIC PLC | Sell | −245,332 | −0.47 |
| ≡ | SEPN – SEPTERNA INC | Buy | 750,000 | 0.47 |
| ≡ | INTRA-CELLULAR THERAPIES INC | Reduce 21.00% | −333,887 | 0.42 |
| ≡ | IRON – DISC MEDICINE INC | Sell | −387,017 | −0.40 |
| ≡ | DRUG – BRIGHT MINDS BIOSCIENCES INC | Buy | 403,649 | 0.40 |
| ≡ | ARCELLX INC | Reduce 11.00% | −409,781 | 0.39 |
| ≡ | OCUL – OCULAR THERAPEUTIX INC | Reduce 68.00% | −2,245,973 | −0.36 |
| ≡ | MRUS 10/21/22 P30 – MERUS N V | Buy | 300,000 | 0.34 |
| ≡ | AVR – ANTERIS TECHNOLOGIES GLOBAL | Buy | 2,140,000 | 0.32 |
| ≡ | MERUS N V | Sell | −300,000 | −0.32 |
| ≡ | ISRG – INTUITIVE SURGICAL INC | Add 9.00% | 5,000 | 0.29 |
| ≡ | EW – EDWARDS LIFESCIENCES CORP | Buy | 145,000 | 0.29 |
| ≡ | ICLR – ICON PLC | Sell | −44,353 | −0.27 |
| ≡ | ARQT – ARCUTIS BIOTHERAPEUTICS INC | Sell | −1,358,500 | −0.27 |
| ≡ | CGON – CG ONCOLOGY INC | Reduce 43.00% | −314,245 | −0.26 |
| ≡ | TYRA – TYRA BIOSCIENCES INC | Sell | −511,226 | −0.25 |
| ≡ | RAPT 05/21/21 C35 – RAPT THERAPEUTICS INC | Buy | 5,880,000 | 0.25 |
| ≡ | INARI MED INC | Buy | 178,797 | 0.25 |
| ≡ | ZENAS BIOPHARMA INC | Reduce 35.00% | −400,000 | −0.24 |
| ≡ | ONKURE THERAPEUTICS INC | Buy | 1,004,439 | 0.23 |
| ≡ | RCKT – ROCKET PHARMACEUTICALS INC | Reduce 59.00% | −553,267 | −0.23 |
| ≡ | ARGX – ARGENX SE | Reduce 43.00% | −51,368 | −0.23 |
| ≡ | XNCR – XENCOR INC | Sell | −527,671 | −0.22 |
| ≡ | ROIV – ROIVANT SCIENCES LTD | Sell | −847,745 | −0.21 |
| ≡ | AVBP – ARRIVENT BIOPHARMA INC | Sell | −415,000 | −0.21 |
| ≡ | DYN – DYNE THERAPEUTICS INC | Reduce 24.00% | −174,867 | −0.20 |
| ≡ | ORKA – ORUKA THERAPEUTICS INC | Reduce 32.00% | −389,620 | −0.19 |
| ≡ | EXACT SCIENCES CORP | Sell | −125,000 | −0.18 |
| ≡ | RAPP – RAPPORT THERAPEUTICS INC | Reduce 58.00% | −436,632 | −0.17 |
| ≡ | PEPG – PEPGEN INC | Reduce 41.00% | −580,902 | −0.17 |
| ≡ | NRIX – NURIX THERAPEUTICS INC | Buy | 330,614 | 0.17 |
| ≡ | ALLO – ALLOGENE THERAPEUTICS INC | Sell | −2,725,000 | −0.16 |
| ≡ | SYRE – SPYRE THERAPEUTICS INC | Reduce 10.00% | −297,824 | −0.16 |
| ≡ | VRCA – VERRICA PHARMACEUTICALS INC | Reduce 54.00% | −3,849,513 | −0.16 |
| ≡ | VERONA PHARMA PLC | Sell | −250,000 | −0.15 |
| ≡ | VERONA PHARMA PLC | Sell | −250,000 | −0.15 |
| ≡ | ARVN – ARVINAS INC | Reduce 28.00% | −287,000 | −0.15 |
| ≡ | NBIX – NEUROCRINE BIOSCIENCES | Reduce 53.00% | −112,178 | −0.15 |
| ≡ | AKERO THERAPEUTICS INC | Reduce 31.00% | −529,214 | −0.14 |
| ≡ | IMTX – IMMATICS N.V | Add 16.00% | 1,297,297 | −0.14 |
| ≡ | EYPT – EYEPOINT PHARMACEUTICALS INC | Add 48.00% | 500,000 | 0.14 |
| ≡ | CERIBELL INC | Buy | 180,546 | 0.13 |
| ≡ | AMICUS THERAPEUTICS INC | Reduce 14.00% | −3,811,504 | −0.13 |
| ≡ | IRTC – IRHYTHM TECHNOLOGIES INC | Add 188.00% | 42,562 | 0.12 |
| ≡ | FLNAPUT – CASSAVA SCIENCES INC | Sell | −183,000 | −0.11 |
| ≡ | FULCCALL – FULCRUM THERAPEUTICS INC | Sell | −1,500,000 | −0.11 |
| ≡ | PERSPECTIVE THERAPEUTICS INC | Buy | 1,190,263 | 0.10 |
| ≡ | PRCT – PROCEPT BIOROBOTICS CORP | Reduce 8.00% | −25,000 | 0.10 |
| ≡ | LINEAGE CELL THERAPEUTICS IN | Buy | 7,236,843 | 0.10 |
| ≡ | XENE – XENON PHARMACEUTICALS INC | Reduce 38.00% | −199,606 | −0.09 |
| ≡ | ATHA 04/16/21 P15 – ATHIRA PHARMA INC | Buy | 5,402,964 | 0.09 |
| ≡ | IMMUNITYBIO INC | Buy | 1,221,734 | 0.09 |
| ≡ | DTIL – PRECISION BIOSCIENCES INC | Sell | −426,293 | −0.08 |
| ≡ | ABSI – ABSCI CORPORATION | Sell | −700,000 | −0.06 |
| ≡ | NTRA – NATERA INC | Reduce 43.00% | −95,000 | −0.05 |
| ≡ | ATHIRA PHARMA INC | Sell | −5,402,964 | −0.05 |
| ≡ | ASNSUSD – X4 PHARMACEUTICALS INC | Sell | −3,545,454 | −0.05 |
| ≡ | NVNO – ENVVENO MEDICAL CORPORATION | Sell | −694,315 | −0.05 |
| ≡ | SCPHARMACEUTICALS INC | Buy | 500,000 | 0.05 |
| ≡ | BCYC – BICYCLE THERAPEUTICS PLC | Reduce 23.00% | −58,886 | −0.05 |
| ≡ | NBTX – NANOBIOTIX | Reduce 52.00% | −288,973 | −0.05 |
| ≡ | KYMR – KYMERA THERAPEUTICS INC | Sell | −46,213 | −0.05 |
| ≡ | AXSM – AXSOME THERAPEUTICS INC | Reduce 15.00% | −118,770 | 0.04 |
| ≡ | TRAWS PHARMA INC | Buy | 164,157 | 0.04 |
| ≡ | ADMA – ADMA BIOLOGICS INC | Reduce 16.00% | −169,920 | −0.03 |
| ≡ | MREO – MEREO BIOPHARMA GROUP PLC | Add 33.00% | 269,790 | 0.03 |
| ≡ | STRUCTURE THERAPEUTICS INC | Sell | −34,852 | −0.03 |
| ≡ | PYXS – PYXIS ONCOLOGY INC | Reduce 63.00% | −320,000 | −0.03 |
| ≡ | FULC – FULCRUM THERAPEUTICS INC | Buy | 238,000 | 0.03 |
| ≡ | PTGX – PROTAGONIST THERAPEUTICS INC | Reduce 7.00% | −102,901 | 0.03 |
| ≡ | FATE – FATE THERAPEUTICS INC | Sell | −345,575 | −0.03 |
| ≡ | ENSC – ENSYSCE BIOSCIENCES INC | Buy | 86,666 | 0.02 |
| ≡ | SINGULAR GENOMICS SYSTEMS IN | Sell | −50,896 | −0.02 |
| ≡ | DELCATH SYS INC | Buy | 50,000 | 0.02 |
| ≡ | KYTX – KYVERNA THERAPEUTICS INC | Sell | −150,000 | −0.02 |
| ≡ | INSM – INSMED INC | Reduce 20.00% | −36,000 | −0.01 |
| ≡ | IMVT – IMMUNOVANT INC | Reduce 10.00% | −239,563 | 0.01 |
| ≡ | APYX – APYX MEDICAL CORPORATION | Buy | 150,000 | 0.01 |
| ≡ | SYRS – SYROS PHARMACEUTICALS INC | Sell | −116,754 | −0.01 |
| ≡ | VERU – VERU INC | Reduce 11.00% | −800,000 | −0.00 |
| ≡ | CAREMAX INC | Sell | −100,000 | −0.00 |
| ≡ | CAREMAX INC | Sell | −60,000 | −0.00 |
| ≡ |
| NBIX – NEUROCRINE BIOSCIENCES INC |
| Reduce 67.00% |
| −437,681 |
| −1.64 |
| ≡ | PCVX – VAXCYTE INC | Add 9.00% | 165,000 | 1.51 |
| ≡ | VKTX – VIKING THERAPEUTICS INC | Add 136.00% | 978,610 | 1.35 |
| ≡ | CENTESSA PHARMACEUTICALS PLC | Add 60.00% | 2,348,983 | 1.27 |
| ≡ | ARGX – ARGENX SE | Add 662.00% | 103,239 | 1.20 |
| ≡ | SPRINGWORKS THERAPEUTICS INC | Reduce 58.00% | −960,699 | −1.03 |
| ≡ | VRDN – VIRIDIAN THERAPEUTICS INC | Add 72.00% | 1,180,837 | 0.84 |
| ≡ | XBIPUT – SPDR SER TR | Buy | 400,000 | 0.84 |
| ≡ | CRNX – CRINETICS PHARMACEUTICALS IN | Reduce 51.00% | −751,505 | −0.81 |
| ≡ | NTRA – NATERA INC | Reduce 58.00% | −310,000 | −0.79 |
| ≡ | BBIO – BRIDGEBIO PHARMA INC | Sell | −1,215,346 | −0.74 |
| ≡ | PODD – INSULET CORP | Buy | 142,269 | 0.70 |
| ≡ | PRAX – PRAXIS PRECISION MEDICINES I | Add 55.00% | 413,805 | 0.67 |
| ≡ | ORKA – ORUKA THERAPEUTICS INC | Buy | 1,235,187 | 0.64 |
| ≡ | AXSM – AXSOME THERAPEUTICS INC | Add 71.00% | 323,733 | 0.60 |
| ≡ | DYN – DYNE THERAPEUTICS INC | Buy | 718,144 | 0.55 |
| ≡ | ADGM – ADAGIO MED HLDGS INC | Buy | 9,812,419 | 0.54 |
| ≡ | EWTX – EDGEWISE THERAPEUTICS INC | Add 26.00% | 473,877 | 0.51 |
| ≡ | INSTIL BIO INC | Buy | 345,545 | 0.49 |
| ≡ | MDT – MEDTRONIC PLC | Reduce 50.00% | −245,333 | −0.46 |
| ≡ | ZENAS BIOPHARMA INC | Buy | 1,144,035 | 0.41 |
| ≡ | EOLS – EVOLUS INC | Reduce 7.00% | −397,176 | 0.33 |
| ≡ | CGEM – CULLINAN THERAPEUTICS INC | Sell | −749,916 | −0.32 |
| ≡ | ADMA – ADMA BIOLOGICS INC | Reduce 62.00% | −1,710,800 | −0.30 |
| ≡ | RCKT – ROCKET PHARMACEUTICALS INC | Reduce 25.00% | −314,746 | −0.28 |
| ≡ | PTGX – PROTAGONIST THERAPEUTICS INC | Add 8.00% | 105,828 | 0.25 |
| ≡ | ZYME – ZYMEWORKS INC | Add 31.00% | 512,309 | 0.24 |
| ≡ | TEM – TEMPUS AI INC | Sell | −275,000 | −0.23 |
| ≡ | PRCT – PROCEPT BIOROBOTICS CORP | Add 50.00% | 105,000 | 0.22 |
| ≡ | XNCR – XENCOR INC | Buy | 527,671 | 0.22 |
| ≡ | IMVT – IMMUNOVANT INC | Add 24.00% | 454,976 | 0.21 |
| ≡ | ROIV – ROIVANT SCIENCES LTD | Buy | 847,745 | 0.21 |
| ≡ | IRON – DISC MEDICINE INC | Reduce 30.00% | −166,420 | −0.20 |
| ≡ | AKERO THERAPEUTICS INC | Add 14.00% | 214,909 | 0.19 |
| ≡ | ENGN – ENGENE HOLDINGS INC | Sell | −800,000 | −0.18 |
| ≡ | EXACT SCIENCES CORP | Buy | 125,000 | 0.18 |
| ≡ | SPRY – ARS PHARMACEUTICALS INC | Sell | −867,319 | −0.18 |
| ≡ | BCYC – BICYCLE THERAPEUTICS PLC | Reduce 55.00% | −316,006 | −0.16 |
| ≡ | VERONA PHARMA PLC | Buy | 250,000 | 0.15 |
| ≡ | VERONA PHARMA PLC | Buy | 250,000 | 0.15 |
| ≡ | AMLX – AMYLYX PHARMACEUTICALS INC | Buy | 2,125,649 | 0.15 |
| ≡ | KALVISTA PHARMACEUTICALS INC | Sell | −500,000 | −0.14 |
| ≡ | RXRX – RECURSION PHARMACEUTICALS IN | Sell | −769,230 | −0.14 |
| ≡ | TYRA – TYRA BIOSCIENCES INC | Reduce 49.00% | −496,141 | −0.13 |
| ≡ | IMVTCALL – IMMUNOVANT INC | Sell | −200,000 | −0.13 |
| ≡ | FULCCALL – FULCRUM THERAPEUTICS INC | Buy | 1,500,000 | 0.11 |
| ≡ | XENE – XENON PHARMACEUTICALS INC | Reduce 10.00% | −58,326 | −0.11 |
| ≡ | CABA – CABALETTA BIO INC | Sell | −585,045 | −0.11 |
| ≡ | SKYE BIOSCIENCE INC | Sell | −500,000 | −0.10 |
| ≡ | ARQT – ARCUTIS BIOTHERAPEUTICS INC | Reduce 13.00% | −200,000 | −0.08 |
| ≡ | FHTX – FOGHORN THERAPEUTICS INC | Sell | −544,000 | −0.08 |
| ≡ | ISRG – INTUITIVE SURGICAL INC | Reduce 6.00% | −3,681 | −0.06 |
| ≡ | IRTC – IRHYTHM TECHNOLOGIES INC | Reduce 36.00% | −12,614 | −0.06 |
| ≡ | XBI – SPDR SER TR | Sell | −22,665 | −0.05 |
| ≡ | KYMR – KYMERA THERAPEUTICS INC | Buy | 46,213 | 0.05 |
| ≡ | EYPT – EYEPOINT PHARMACEUTICALS INC | Add 62.00% | 397,000 | 0.04 |
| ≡ | PYXS – PYXIS ONCOLOGY INC | Buy | 508,462 | 0.04 |
| ≡ | MEIRAGTX HLDGS PLC | Add 11.00% | 1,250,000 | −0.04 |
| ≡ | MREO – MEREO BIOPHARMA GROUP PLC | Reduce 35.00% | −437,528 | −0.04 |
| ≡ | REVANCE THERAPEUTICS INC | Sell | −600,000 | −0.04 |
| ≡ | ICLR – ICON PLC | Add 42.00% | 13,103 | 0.03 |
| ≡ | FBRX – FORTE BIOSCIENCES INC | Reduce 97.00% | −3,169,617 | −0.03 |
| ≡ | NVNO – ENVVENO MEDICAL CORPORATION | Add 11.00% | 71,000 | −0.03 |
| ≡ | LXEO – LEXEO THERAPEUTICS INC | Buy | 139,835 | 0.03 |
| ≡ | EGRX – EAGLE PHARMACEUTICALS INC | Sell | −173,365 | −0.02 |
| ≡ | VBI VACCINES INC CDA | Sell | −1,261,710 | −0.02 |
| ≡ | TCMD – TACTILE SYS TECHNOLOGY INC | Sell | −62,639 | −0.02 |
| ≡ | AXGN – AXOGEN INC | Sell | −30,421 | −0.01 |
| ≡ | CAREMAX INC | Reduce 18.00% | −22,643 | −0.00 |
| ≡ | SINGULAR GENOMICS SYSTEMS IN | Reduce 28.00% | −20,000 | 0.00 |
| ≡ | OBIO – ORCHESTRA BIOMED HLDGS INC | Add 80.00% | 2,046,675 | −0.00 |
| MDT – MEDTRONIC PLC |
| Reduce 66.00% |
| −938,898 |
| −1.25 |
| ≡ | SRPT – SAREPTA THERAPEUTICS INC | Sell | −525,683 | −1.19 |
| ≡ | NUVALENT INC | Reduce 8.00% | −234,377 | 1.00 |
| ≡ | CTNM – CONTINEUM THERAPEUTICS INC | Buy | 1,566,668 | 0.66 |
| ≡ | AXSM – AXSOME THERAPEUTICS INC | Reduce 58.00% | −646,230 | −0.65 |
| ≡ | VRDN – VIRIDIAN THERAPEUTICS INC | Reduce 55.00% | −2,025,271 | −0.61 |
| ≡ | LANDOS BIOPHARMA INC | Sell | −1,486,991 | −0.56 |
| ≡ | PTGX – PROTAGONIST THERAPEUTICS INC | Add 28.00% | 274,412 | 0.56 |
| ≡ | TMCI – TREACE MED CONCEPTS INC | Sell | −2,304,954 | −0.53 |
| ≡ | VKTX – VIKING THERAPEUTICS INC | Reduce 27.00% | −272,721 | −0.51 |
| ≡ | AUTL – AUTOLUS THERAPEUTICS PLC | Sell | −4,330,745 | −0.48 |
| ≡ | IMVT – IMMUNOVANT INC | Reduce 35.00% | −1,039,426 | −0.45 |
| ≡ | SPRINGWORKS THERAPEUTICS INC | Reduce 27.00% | −609,500 | −0.45 |
| ≡ | CGON – CG ONCOLOGY INC | Reduce 44.00% | −570,410 | −0.44 |
| ≡ | MERUS N V | Buy | 300,000 | 0.43 |
| ≡ | IRON – DISC MEDICINE INC | Reduce 41.00% | −386,429 | −0.42 |
| ≡ | RAPP – RAPPORT THERAPEUTICS INC | Buy | 748,183 | 0.42 |
| ≡ | BHVN – BIOHAVEN LTD | Reduce 14.00% | −239,815 | −0.41 |
| ≡ | CABA – CABALETTA BIO INC | Reduce 66.00% | −1,131,615 | −0.41 |
| ≡ | IRTC – IRHYTHM TECHNOLOGIES INC | Reduce 86.00% | −210,000 | −0.41 |
| ≡ | ACRV – ACRIVON THERAPEUTICS INC | Add 78.00% | 2,353,000 | 0.37 |
| ≡ | INBX – INHIBRX BIOSCIENCES INC | Buy | 1,064,026 | 0.36 |
| ≡ | RVMD – REVOLUTION MEDICINES INC | Sell | −618,885 | −0.35 |
| ≡ | ABBV – ABBVIE INC | Sell | −106,500 | −0.34 |
| ≡ | IRONPUT – DISC MEDICINE INC | Sell | −300,000 | −0.33 |
| ≡ | CGEM – CULLINAN THERAPEUTICS INC | Buy | 749,916 | 0.32 |
| ≡ | MLTX – MOONLAKE IMMUNOTHERAPEUTICS | Sell | −339,012 | −0.30 |
| ≡ | LIVN – LIVANOVA PLC | Add 48.00% | 145,000 | 0.29 |
| ≡ | INSM – INSMED INC | Buy | 180,000 | 0.29 |
| ≡ | BCYC – BICYCLE THERAPEUTICS PLC | Buy | 572,000 | 0.28 |
| ≡ | ALDX – ALDEYRA THERAPEUTICS INC | Add 8.00% | 682,265 | 0.25 |
| ≡ | CENTESSA PHARMACEUTICALS PLC | Add 28.00% | 850,000 | 0.25 |
| ≡ | TCMD – TACTILE SYS TECHNOLOGY INC | Reduce 93.00% | −840,446 | −0.24 |
| ≡ | ICLR – ICON PLC | Buy | 31,250 | 0.24 |
| ≡ | AKERO THERAPEUTICS INC | Add 8.00% | 112,426 | 0.23 |
| ≡ | ARVN – ARVINAS INC | Reduce 17.00% | −208,854 | −0.23 |
| ≡ | TEM – TEMPUS AI INC | Buy | 275,000 | 0.23 |
| ≡ | MDGL – MADRIGAL PHARMACEUTICALS INC | Reduce 38.00% | −165,353 | −0.22 |
| ≡ | ARQT – ARCUTIS BIOTHERAPEUTICS INC | Add 108.00% | 808,500 | 0.22 |
| ≡ | AXGN – AXOGEN INC | Reduce 98.00% | −1,523,508 | −0.21 |
| ≡ | NBIX – NEUROCRINE BIOSCIENCES INC | Reduce 19.00% | −154,500 | 0.21 |
| ≡ | VERONA PHARMA PLC | Reduce 35.00% | −1,327,851 | −0.21 |
| ≡ | RCKT – ROCKET PHARMACEUTICALS INC | Reduce 31.00% | −554,471 | −0.20 |
| ≡ | TYRA – TYRA BIOSCIENCES INC | Add 51.00% | 338,208 | 0.20 |
| ≡ | RAPT THERAPEUTICS INC | Sell | −1,223,472 | −0.19 |
| ≡ | MORPHIC HLDG INC | Sell | −288,221 | −0.18 |
| ≡ | NTRA – NATERA INC | Reduce 30.00% | −227,225 | 0.17 |
| ≡ | ARGX – ARGENX SE | Buy | 15,600 | 0.16 |
| ≡ | ALLO – ALLOGENE THERAPEUTICS INC | Buy | 2,725,000 | 0.15 |
| ≡ | ZYME – ZYMEWORKS INC | Add 55.00% | 592,904 | 0.14 |
| ≡ | RXRX – RECURSION PHARMACEUTICALS IN | Buy | 769,230 | 0.14 |
| ≡ | PRAX – PRAXIS PRECISION MEDICINES I | Reduce 9.00% | −71,359 | −0.13 |
| ≡ | XENE – XENON PHARMACEUTICALS INC | Reduce 35.00% | −308,952 | −0.12 |
| ≡ | ENGN – ENGENE HOLDINGS INC | Reduce 20.00% | −198,888 | −0.11 |
| ≡ | CARGO THERAPEUTICS INC | Add 7.00% | 235,000 | 0.11 |
| ≡ | MREO – MEREO BIOPHARMA GROUP PLC | Buy | 1,253,250 | 0.11 |
| ≡ | COGT – COGENT BIOSCIENCES INC | Sell | −883,333 | −0.10 |
| ≡ | IMMUNITYBIO INC | Sell | −1,052,887 | −0.10 |
| ≡ | MGNX – MACROGENICS INC | Sell | −378,327 | −0.10 |
| ≡ | SKYE BIOSCIENCE INC | Buy | 500,000 | 0.10 |
| ≡ | AMLXCALL – AMYLYX PHARMACEUTICALS INC | Sell | −1,679,125 | −0.08 |
| ≡ | XBIPUT – SPDR SER TR | Sell | −50,000 | −0.08 |
| ≡ | BDSX – BIODESIX INC | Buy | 2,173,880 | 0.08 |
| ≡ | EYPT – EYEPOINT PHARMACEUTICALS INC | Add 9.00% | 50,628 | −0.08 |
| ≡ | FHTX – FOGHORN THERAPEUTICS INC | Buy | 544,000 | 0.08 |
| ≡ | VERU – VERU INC | Add 26.00% | 1,478,578 | 0.07 |
| ≡ | ESTABLISHMENT LABS HLDGS INC | Sell | −82,299 | −0.07 |
| ≡ | NAMS – NEWAMSTERDAM PHARMA COMPANY | Sell | −175,000 | −0.07 |
| ≡ | IMVTCALL – IMMUNOVANT INC | Add 100.00% | 100,000 | 0.07 |
| ≡ | EWTX – EDGEWISE THERAPEUTICS INC | Reduce 20.00% | −463,229 | 0.07 |
| ≡ | APPLIED THERAPEUTICS INC | Sell | −500,000 | −0.06 |
| ≡ | FLNAPUT – CASSAVA SCIENCES INC | Buy | 183,000 | 0.05 |
| ≡ | AGIOCALL – AGIOS PHARMACEUTICALS INC | Sell | −100,000 | −0.05 |
| ≡ | XBI – SPDR SER TR | Buy | 22,665 | 0.05 |
| ≡ | ISRG – INTUITIVE SURGICAL INC | Reduce 39.00% | −40,000 | −0.05 |
| ≡ | STRUCTURE THERAPEUTICS INC | Buy | 34,852 | 0.03 |
| ≡ | NVAXPUT – NOVAVAX INC | Reduce 86.00% | −600,000 | −0.03 |
| ≡ | FATE – FATE THERAPEUTICS INC | Buy | 345,575 | 0.03 |
| ≡ | EGRX – EAGLE PHARMACEUTICALS INC | Buy | 173,365 | 0.02 |
| ≡ | BBIO – BRIDGEBIO PHARMA INC | Reduce 14.00% | −196,687 | −0.02 |
| ≡ | SYRE – SPYRE THERAPEUTICS INC | Add 19.00% | 474,339 | 0.02 |
| ≡ | SINGULAR GENOMICS SYSTEMS IN | Sell | −2,126,893 | −0.02 |
| ≡ | KURA ONCOLOGY INC | Sell | −48,200 | −0.02 |
| ≡ | AMLX – AMYLYX PHARMACEUTICALS INC | Sell | −300,000 | −0.01 |
| ≡ | SINGULAR GENOMICS SYSTEMS IN | Buy | 70,896 | 0.01 |
| ≡ | DTIL – PRECISION BIOSCIENCES INC | Reduce 11.00% | −54,190 | −0.01 |
| ≡ | IOVA – IOVANCE BIOTHERAPEUTICS INC | Add 35.00% | 6,660,151 | 0.01 |
| ≡ | ADMA – ADMA BIOLOGICS INC | Reduce 57.00% | −3,662,369 | 0.00 |
| ≡ |
| VKTX – VIKING THERAPEUTICS INC |
| Buy |
| 994,098 |
| 1.43 |
| ≡ | APGE – APOGEE THERAPEUTICS INC | Add 13.00% | 232,494 | 1.26 |
| ≡ | MDGL – MADRIGAL PHARMACEUTICALS INC | Add 184.00% | 278,802 | 1.23 |
| ≡ | NBIX – NEUROCRINE BIOSCIENCES INC | Add 197.00% | 533,615 | 1.14 |
| ≡ | SLDB – SOLID BIOSCIENCES INC | Add 98.00% | 3,410,713 | 1.13 |
| ≡ | INTRA-CELLULAR THERAPIES INC | Add 877.00% | 947,355 | 1.11 |
| ≡ | RAYZEBIO INC | Sell | −744,056 | −1.03 |
| ≡ | CGON – CG ONCOLOGY INC | Buy | 1,304,105 | 1.00 |
| ≡ | RAPT THERAPEUTICS INC | Reduce 43.00% | −916,478 | −0.99 |
| ≡ | ASTRIA THERAPEUTICS INC | Add 62.00% | 2,481,350 | 0.91 |
| ≡ | PRAX – PRAXIS PRECISION MEDICINES I | Buy | 821,589 | 0.88 |
| ≡ | ARCELLX INC | Reduce 13.00% | −611,253 | −0.84 |
| ≡ | BBIO – BRIDGEBIO PHARMA INC | Reduce 19.00% | −336,900 | −0.81 |
| ≡ | PCVX – VAXCYTE INC | Add 78.00% | 844,273 | 0.78 |
| ≡ | APPLIED THERAPEUTICS INC | Add 96.00% | 3,924,751 | 0.65 |
| ≡ | AORT – ARTIVION INC | Add 187.00% | 1,737,626 | 0.62 |
| ≡ | CENTESSA PHARMACEUTICALS PLC | Buy | 3,083,307 | 0.61 |
| ≡ | EWTX – EDGEWISE THERAPEUTICS INC | Add 318.00% | 1,764,091 | 0.60 |
| ≡ | AMLX – AMYLYX PHARMACEUTICALS INC | Reduce 84.00% | −1,569,125 | −0.60 |
| ≡ | ARVN – ARVINAS INC | Add 249.00% | 882,521 | 0.57 |
| ≡ | OCUL – OCULAR THERAPEUTIX INC | Buy | 3,324,468 | 0.53 |
| ≡ | IMVT – IMMUNOVANT INC | Add 27.00% | 635,130 | −0.51 |
| ≡ | CABA – CABALETTA BIO INC | Reduce 14.00% | −286,398 | −0.50 |
| ≡ | IRTC – IRHYTHM TECHNOLOGIES INC | Buy | 245,205 | 0.50 |
| ≡ | ABBV – ABBVIE INC | Reduce 55.00% | −131,500 | −0.48 |
| ≡ | EOLS – EVOLUS INC | Add 45.00% | 1,790,374 | 0.48 |
| ≡ | XENE – XENON PHARMACEUTICALS INC | Reduce 19.00% | −208,540 | −0.46 |
| ≡ | CELC – CELCUITY INC | Add 59.00% | 880,979 | 0.41 |
| ≡ | MDT – MEDTRONIC PLC | Add 46.00% | 452,911 | 0.38 |
| ≡ | ASND – ASCENDIS PHARMAA/S | Sell | −132,176 | −0.37 |
| ≡ | PEPG – PEPGEN INC | Buy | 1,410,438 | 0.36 |
| ≡ | SPRINGWORKS THERAPEUTICS INC | Add 16.00% | 305,216 | 0.35 |
| ≡ | MIRM – MIRUM PHARMACEUTICALS INC | Sell | −534,942 | −0.35 |
| ≡ | IRONPUT – DISC MEDICINE INC | Buy | 300,000 | 0.33 |
| ≡ | PTGX – PROTAGONIST THERAPEUTICS INC | Add 159.00% | 611,063 | 0.31 |
| ≡ | AXSM – AXSOME THERAPEUTICS INC | Add 6.00% | 67,322 | −0.30 |
| ≡ | ISRG – INTUITIVE SURGICAL INC | Add 85.00% | 46,800 | 0.30 |
| ≡ | ENGN – ENGENE HOLDINGS INC | Buy | 998,888 | 0.30 |
| ≡ | IRON – DISC MEDICINE INC | Reduce 8.00% | −83,179 | −0.30 |
| ≡ | LIVN – LIVANOVA PLC | Buy | 299,000 | 0.29 |
| ≡ | VRDN – VIRIDIAN THERAPEUTICS INC | Add 111.00% | 1,926,887 | 0.28 |
| ≡ | RYTM – RHYTHM PHARMACEUTICALS INC | Add 52.00% | 1,114,469 | 0.27 |
| ≡ | TNGX – TANGO THERAPEUTICS INC | Sell | −1,111,870 | −0.25 |
| ≡ | AUTL – AUTOLUS THERAPEUTICS PLC | Add 137.00% | 2,499,578 | 0.22 |
| ≡ | SRPT – SAREPTA THERAPEUTICS INC | Add 16.00% | 73,810 | 0.22 |
| ≡ | CRNX – CRINETICS PHARMACEUTICALS IN | Add 18.00% | 220,691 | 0.21 |
| ≡ | MLTX – MOONLAKE IMMUNOTHERAPEUTICS | Add 311.00% | 256,614 | 0.19 |
| ≡ | PRCT – PROCEPT BIOROBOTICS CORP | Buy | 210,659 | 0.18 |
| ≡ | RVMD – REVOLUTION MEDICINES INC | Reduce 24.00% | −199,997 | −0.18 |
| ≡ | TMCI – TREACE MED CONCEPTS INC | Add 84.00% | 1,054,549 | 0.17 |
| ≡ | OLMA – OLEMA PHARMACEUTICALS INC | Sell | −539,831 | −0.17 |
| ≡ | TERNS PHARMACEUTICALS INC | Sell | −1,075,000 | −0.16 |
| ≡ | SPRY – ARS PHARMACEUTICALS INC | Buy | 867,319 | 0.16 |
| ≡ | MORPHIC HLDG INC | Add 406.00% | 231,241 | 0.14 |
| ≡ | RGNX – REGENXBIO INC | Sell | −342,408 | −0.14 |
| ≡ | ARQT – ARCUTIS BIOTHERAPEUTICS INC | Buy | 750,000 | 0.13 |
| ≡ | AVBP – ARRIVENT BIOPHARMA INC | Buy | 415,000 | 0.13 |
| ≡ | DTIL – PRECISION BIOSCIENCES INC | Buy | 480,483 | 0.11 |
| ≡ | AKERO THERAPEUTICS INC | Add 43.00% | 419,696 | 0.11 |
| ≡ | KALVISTA PHARMACEUTICALS INC | Buy | 500,000 | 0.10 |
| ≡ | IMMUNITYBIO INC | Buy | 1,052,887 | 0.10 |
| ≡ | AXGN – AXOGEN INC | Add 92.00% | 745,549 | 0.10 |
| ≡ | BBOT – HELIX ACQUISITION CORP II | Buy | 500,000 | 0.09 |
| ≡ | AMLXCALL – AMYLYX PHARMACEUTICALS INC | Buy | 1,679,125 | 0.08 |
| ≡ | TYRA – TYRA BIOSCIENCES INC | Add 86.00% | 309,159 | 0.08 |
| ≡ | TVTX – TRAVERE THERAPEUTICS INC | Sell | −400,000 | −0.08 |
| ≡ | NAMS – NEWAMSTERDAM PHARMA COMPANY | Buy | 175,000 | 0.07 |
| ≡ | ACAD – ACADIA PHARMACEUTICALS INC | Sell | −101,000 | −0.07 |
| ≡ | ABSI – ABSCI CORPORATION | Buy | 700,000 | 0.07 |
| ≡ | KYTX – KYVERNA THERAPEUTICS INC | Buy | 150,000 | 0.07 |
| ≡ | TRIB – TRINITY BIOTECH PLC | Buy | 1,800,000 | 0.06 |
| ≡ | IMVTCALL – IMMUNOVANT INC | Buy | 100,000 | 0.06 |
| ≡ | CYTK – CYTOKINETICS INC | Sell | −30,317 | −0.06 |
| ≡ | XBIPUT – SPDR SER TR | Reduce 97.00% | −1,850,000 | 0.05 |
| ≡ | REVANCE THERAPEUTICS INC | Buy | 600,000 | 0.05 |
| ≡ | AGIOCALL – AGIOS PHARMACEUTICALS INC | Buy | 100,000 | 0.05 |
| ≡ | KRONOS BIO INC | Sell | −1,752,745 | −0.05 |
| ≡ | NVAXPUT – NOVAVAX INC | Reduce 50.00% | −700,000 | −0.05 |
| ≡ | COGT – COGENT BIOSCIENCES INC | Reduce 21.00% | −239,625 | −0.04 |
| ≡ | CAREMAX INC | Sell | −3,679,284 | −0.04 |
| ≡ | MGNX – MACROGENICS INC | Reduce 38.00% | −233,605 | −0.03 |
| ≡ | TCMD – TACTILE SYS TECHNOLOGY INC | Add 28.00% | 195,926 | 0.03 |
| ≡ | AMBRX BIOPHARMA INC | Sell | −78,811 | −0.03 |
| ≡ | NTRA – NATERA INC | Reduce 11.00% | −93,000 | 0.02 |
| ≡ | IMTX – IMMATICS N.V | Add 31.00% | 1,090,909 | 0.02 |
| ≡ | KURA ONCOLOGY INC | Buy | 48,200 | 0.02 |
| ≡ | SYRS – SYROS PHARMACEUTICALS INC | Buy | 116,754 | 0.01 |
| ≡ | CAREMAX INC | Buy | 122,643 | 0.01 |
| ≡ | VBI VACCINES INC CDA | Reduce 9.00% | −119,645 | −0.00 |
| ≡ | CYPH – LEAP THERAPEUTICS INC | Sell | −44,971 | −0.00 |
| ≡ | BCABGBP – BIOATLA INC | Sell | −73,000 | −0.00 |
| ≡ | EYPTPUT – EYEPOINT PHARMACEUTICALS INC | Sell | −750,000 | −0.00 |
| ≡ |
| RYTM – RHYTHM PHARMACEUTICALS INC |
| Add 466.00% |
| 1,773,282 |
| 1.92 |
| ≡ | ALDX – ALDEYRA THERAPEUTICS INC | Reduce 24.00% | −2,756,499 | −1.86 |
| ≡ | CARGO THERAPEUTICS INC | Buy | 3,436,600 | 1.78 |
| ≡ | ROIV – ROIVANT SCIENCES LTD | Sell | −3,819,456 | −1.49 |
| ≡ | SYRE – SPYRE THERAPEUTICS INC | Add 3114.00% | 2,525,563 | 1.22 |
| ≡ | HRMY – HARMONY BIOSCIENCES HLDGS IN | Sell | −996,306 | −1.09 |
| ≡ | AMLX – AMYLYX PHARMACEUTICALS INC | Reduce 30.00% | −819,748 | −1.03 |
| ≡ | NUVALENT INC | Add 18.00% | 454,540 | 1.02 |
| ≡ | BHVN – BIOHAVEN LTD | Add 129.00% | 973,227 | 1.00 |
| ≡ | ARCELLX INC | Add 15.00% | 578,831 | 0.88 |
| ≡ | NTRA – NATERA INC | Add 290.00% | 632,047 | 0.87 |
| ≡ | ABBV – ABBVIE INC | Buy | 238,000 | 0.82 |
| ≡ | PCVX – VAXCYTE INC | Reduce 19.00% | −254,265 | −0.76 |
| ≡ | AXSM – AXSOME THERAPEUTICS INC | Add 116.00% | 556,370 | 0.72 |
| ≡ | RVMD – REVOLUTION MEDICINES INC | Reduce 38.00% | −502,913 | −0.70 |
| ≡ | TNGX – TANGO THERAPEUTICS INC | Reduce 54.00% | −1,307,098 | −0.66 |
| ≡ | COGT – COGENT BIOSCIENCES INC | Reduce 51.00% | −1,186,512 | −0.60 |
| ≡ | RLAY – RELAY THERAPEUTICS INC | Sell | −1,943,097 | −0.55 |
| ≡ | VRCA – VERRICA PHARMACEUTICALS INC | Add 41.00% | 2,060,199 | 0.51 |
| ≡ | CELC – CELCUITY INC | Buy | 1,481,300 | 0.48 |
| ≡ | EOLS – EVOLUS INC | Add 167.00% | 2,477,623 | 0.48 |
| ≡ | TMCI – TREACE MED CONCEPTS INC | Reduce 32.00% | −583,655 | −0.45 |
| ≡ | CABA – CABALETTA BIO INC | Add 77.00% | 870,567 | 0.44 |
| ≡ | XENE – XENON PHARMACEUTICALS INC | Add 78.00% | 483,248 | 0.43 |
| ≡ | SPRINGWORKS THERAPEUTICS INC | Add 29.00% | 436,830 | 0.42 |
| ≡ | ISRG – INTUITIVE SURGICAL INC | Buy | 55,000 | 0.41 |
| ≡ | ESTABLISHMENT LABS HLDGS INC | Reduce 70.00% | −195,384 | −0.41 |
| ≡ | PTGX – PROTAGONIST THERAPEUTICS INC | Reduce 64.00% | −671,013 | −0.39 |
| ≡ | ASND – ASCENDIS PHARMAA/S | Buy | 132,176 | 0.37 |
| ≡ | MIRM – MIRUM PHARMACEUTICALS INC | Reduce 20.00% | −137,100 | −0.36 |
| ≡ | BMEA – BIOMEA FUSION | Sell | −716,441 | −0.33 |
| ≡ | ARVN – ARVINAS INC | Buy | 354,082 | 0.33 |
| ≡ | VRDN – VIRIDIAN THERAPEUTICS INC | Add 71.00% | 719,007 | 0.32 |
| ≡ | APPLIED THERAPEUTICS INC | Buy | 4,080,249 | 0.31 |
| ≡ | EYPT – EYEPOINT PHARMACEUTICALS INC | Buy | 589,646 | 0.30 |
| ≡ | PROTHENA CORP PLC | Sell | −165,615 | −0.27 |
| ≡ | AUTL – AUTOLUS THERAPEUTICS PLC | Buy | 1,831,167 | 0.26 |
| ≡ | MDT – MEDTRONIC PLC | Add 66.00% | 389,652 | 0.26 |
| ≡ | OUTSET MED INC | Sell | −661,977 | −0.24 |
| ≡ | SRPT – SAREPTA THERAPEUTICS INC | Add 147.00% | 269,153 | 0.23 |
| ≡ | NBIX – NEUROCRINE BIOSCIENCES INC | Add 70.00% | 111,552 | 0.20 |
| ≡ | ADMA – ADMA BIOLOGICS INC | Reduce 8.00% | −550,950 | −0.18 |
| ≡ | AKERO THERAPEUTICS INC | Sell | −800,000 | −0.18 |
| ≡ | MDGL – MADRIGAL PHARMACEUTICALS INC | Add 21.00% | 26,514 | 0.17 |
| ≡ | INTRA-CELLULAR THERAPIES INC | Buy | 108,000 | 0.17 |
| ≡ | OLMA – OLEMA PHARMACEUTICALS INC | Buy | 539,831 | 0.17 |
| ≡ | ASTRIA THERAPEUTICS INC | Add 83.00% | 1,814,608 | 0.14 |
| ≡ | RGNX – REGENXBIO INC | Buy | 342,408 | 0.14 |
| ≡ | EWTX – EDGEWISE THERAPEUTICS INC | Buy | 555,555 | 0.14 |
| ≡ | MGNX – MACROGENICS INC | Buy | 611,932 | 0.13 |
| ≡ | RAPT THERAPEUTICS INC | Add 11.00% | 219,292 | 0.12 |
| ≡ | NAUT – NAUTILUS BIOTECHNOLOGY INC | Add 38.00% | 3,483,060 | −0.12 |
| ≡ | SOMALOGIC INC | Sell | −1,500,000 | −0.12 |
| ≡ | MLTX – MOONLAKE IMMUNOTHERAPEUTICS | Buy | 82,398 | 0.11 |
| ≡ | RCKT – ROCKET PHARMACEUTICALS INC | Add 13.00% | 189,931 | 0.11 |
| ≡ | SRPTCALL – SAREPTA THERAPEUTICS INC | Sell | −100,000 | −0.10 |
| ≡ | POINT BIOPHARMA GLOBAL INC | Sell | −800,000 | −0.09 |
| ≡ | ARQTPUT – ARCUTIS BIOTHERAPEUTICS INC | Sell | −300,000 | −0.09 |
| ≡ | IRON – DISC MEDICINE INC | Add 14.00% | 127,404 | −0.08 |
| ≡ | ACAD – ACADIA PHARMACEUTICALS INC | Buy | 101,000 | 0.07 |
| ≡ | NVNO – ENVVENO MEDICAL CORPORATION | Reduce 20.00% | −158,300 | −0.07 |
| ≡ | ACELYRIN INC | Sell | −200,000 | −0.07 |
| ≡ | VERU – VERU INC | Add 412.00% | 4,494,821 | 0.06 |
| ≡ | ZYME – ZYMEWORKS INC | Reduce 26.00% | −371,316 | −0.06 |
| ≡ | CYTK – CYTOKINETICS INC | Buy | 30,317 | 0.06 |
| ≡ | 89BIO INC | Sell | −400,000 | −0.05 |
| ≡ | ACRSPUT – ACLARIS THERAPEUTICS INC | Sell | −500,000 | −0.05 |
| ≡ | MORPHIC HLDGS INC | Buy | 56,980 | 0.04 |
| ≡ | ATHIRA PHARMA INC | Add 13.00% | 605,686 | −0.03 |
| ≡ | XBIPUT – SPDR SER TR | Buy | 1,900,000 | 0.03 |
| ≡ | AMBRX BIOPHARMA INC | Buy | 78,811 | 0.03 |
| ≡ | AXGN – AXOGEN INC | Reduce 8.00% | −67,518 | −0.02 |
| ≡ | NVAXPUT – NOVAVAX INC | Add 8.00% | 100,000 | −0.02 |
| ≡ | APPLIED THERAPEUTICS INC | Buy | 500,000 | 0.01 |
| ≡ | SINGULAR GENOMICS SYSTEMS IN | Reduce 10.00% | −236,321 | −0.01 |
| ≡ | VKTXCALL – VIKING THERAPEUTICS INC | Sell | −300,000 | −0.01 |
| ≡ | BCABGBP – BIOATLA INC | Buy | 73,000 | 0.00 |
| ≡ | APELLIS PHARMACEUTICALS INC | Sell | −100,000 | −0.00 |
| ≡ | REVOLUTION MEDICINES INC | Buy | 250,000 | 0.00 |
| ≡ | MOTUS GI HLDGS INC | Sell | −90,027 | −0.00 |
| ≡ | EQRX INC | Sell | −250,000 | −0.00 |
| ≡ |
| ARGX – ARGENX SE |
| Add 118.00% |
| 81,600 |
| 1.69 |
| ≡ | MDGL – MADRIGAL PHARMACEUTICALS INC | Reduce 59.00% | −178,350 | −1.42 |
| ≡ | AMLX – AMYLYX PHARMACEUTICALS INC | Reduce 45.00% | −2,185,046 | −1.40 |
| ≡ | VIR – VIR BIOTECHNOLOGY INC | Sell | −1,958,264 | −1.39 |
| ≡ | APGE – APOGEE THERAPEUTICS INC | Buy | 1,827,901 | 1.30 |
| ≡ | RVMD – REVOLUTION MEDICINES INC | Buy | 1,321,795 | 1.22 |
| ≡ | NUVALENT INC | Add 12.00% | 268,630 | 1.10 |
| ≡ | IOVA – IOVANCE BIOTHERAPEUTICS INC | Reduce 15.00% | −2,073,472 | −1.04 |
| ≡ | TNGX – TANGO THERAPEUTICS INC | Buy | 2,418,968 | 0.91 |
| ≡ | TMCI – TREACE MED CONCEPTS INC | Reduce 17.00% | −383,190 | −0.84 |
| ≡ | CYMABAY THERAPEUTICS INC | Add 8.00% | 309,936 | 0.83 |
| ≡ | ILMN – ILLUMINA INC | Sell | −145,000 | −0.79 |
| ≡ | MIRATI THERAPEUTICS INC | Sell | −719,103 | −0.75 |
| ≡ | VRDN – VIRIDIAN THERAPEUTICS INC | Reduce 43.00% | −765,181 | −0.71 |
| ≡ | BMRN – BIOMARIN PHARMACEUTICAL INC | Sell | −263,207 | −0.66 |
| ≡ | XENE – XENON PHARMACEUTICALS INC | Reduce 50.00% | −605,877 | −0.66 |
| ≡ | PTGX – PROTAGONIST THERAPEUTICS INC | Reduce 28.00% | −415,488 | −0.59 |
| ≡ | RAYZEBIO INC | Buy | 776,805 | 0.58 |
| ≡ | ROIV – ROIVANT SCIENCES LTD | Add 22.00% | 687,720 | 0.57 |
| ≡ | AXSM – AXSOME THERAPEUTICS INC | Add 77.00% | 210,156 | 0.56 |
| ≡ | VERONA PHARMA PLC | Reduce 9.00% | −389,919 | −0.51 |
| ≡ | SRPT – SAREPTA THERAPEUTICS INC | Add 125.00% | 101,646 | 0.47 |
| ≡ | EOLS – EVOLUS INC | Buy | 1,485,801 | 0.45 |
| ≡ | INTRA-CELLULAR THERAPIES INC | Sell | −245,800 | −0.45 |
| ≡ | IRON – DISC MEDICINE INC | Add 21.00% | 152,803 | 0.45 |
| ≡ | ADMA – ADMA BIOLOGICS INC | Reduce 41.00% | −4,915,936 | −0.44 |
| ≡ | BHVN – BIOHAVEN LTD | Add 134.00% | 431,000 | 0.43 |
| ≡ | ESTABLISHMENT LABS HLDGS INC | Reduce 35.00% | −147,241 | −0.39 |
| ≡ | RCKT – ROCKET PHARMACEUTICALS INC | Add 30.00% | 349,104 | 0.37 |
| ≡ | MDT – MEDTRONIC PLC | Add 26.00% | 120,000 | 0.34 |
| ≡ | OUTSET MED INC | Reduce 27.00% | −240,383 | −0.33 |
| ≡ | NBIX – NEUROCRINE BIOSCIENCES INC | Add 59.00% | 59,192 | 0.32 |
| ≡ | ZYME – ZYMEWORKS INC | Reduce 40.00% | −970,109 | −0.30 |
| ≡ | OBIO – ORCHESTRA BIOMED HLDGS INC | Add 18.00% | 379,221 | 0.29 |
| ≡ | RYTM – RHYTHM PHARMACEUTICALS INC | Buy | 380,828 | 0.29 |
| ≡ | TERNS PHARMACEUTICALS INC | Sell | −1,075,000 | −0.27 |
| ≡ | MIRM – MIRUM PHARMACEUTICALS INC | Add 12.00% | 70,476 | 0.26 |
| ≡ | NTRA – NATERA INC | Reduce 46.00% | −187,091 | −0.25 |
| ≡ | AXGN – AXOGEN INC | Reduce 40.00% | −588,924 | −0.24 |
| ≡ | CRNX – CRINETICS PHARMACEUTICALS IN | Reduce 35.00% | −683,205 | 0.24 |
| ≡ | VKTX – VIKING THERAPEUTICS INC | Sell | −441,147 | −0.21 |
| ≡ | IVERIC BIO INC | Sell | −168,000 | −0.19 |
| ≡ | AKERO THERAPEUTICS INC | Buy | 800,000 | 0.18 |
| ≡ | HRMY – HARMONY BIOSCIENCES HLDGS IN | Add 12.00% | 104,936 | 0.18 |
| ≡ | TERNS PHARMACEUTICALS INC | Buy | 1,075,000 | 0.18 |
| ≡ | RAPT THERAPEUTICS INC | Reduce 16.00% | −367,835 | −0.17 |
| ≡ | COGT – COGENT BIOSCIENCES INC | Reduce 13.00% | −350,000 | −0.16 |
| ≡ | NVAXPUT – NOVAVAX INC | Buy | 1,300,000 | 0.13 |
| ≡ | INHIBRX INC | Add 17.00% | 631,922 | −0.12 |
| ≡ | AKERO THERAPEUTICS INC | Reduce 17.00% | −321,250 | 0.11 |
| ≡ | SRPTCALL – SAREPTA THERAPEUTICS INC | Buy | 100,000 | 0.10 |
| ≡ | TCMD – TACTILE SYS TECHNOLOGY INC | Add 17.00% | 104,782 | −0.10 |
| ≡ | PROTHENA CORP PLC | Reduce 10.00% | −19,000 | −0.10 |
| ≡ | QTRX – QUANTERIX CORP | Sell | −130,000 | −0.08 |
| ≡ | EYPTPUT – EYEPOINT PHARMACEUTICALS INC | Buy | 750,000 | 0.08 |
| ≡ | TVTX – TRAVERE THERAPEUTICS INC | Add 341.00% | 309,252 | 0.08 |
| ≡ | FBRX – FORTE BIOSCIENCES INC | Buy | 3,265,359 | 0.07 |
| ≡ | POINT BIOPHARMA GLOBAL INC | Add 60.00% | 300,000 | 0.07 |
| ≡ | 89BIO INC | Buy | 400,000 | 0.05 |
| ≡ | CYPH – LEAP THERAPEUTICS INC | Reduce 92.00% | −541,762 | −0.05 |
| ≡ | PCVX – VAXCYTE INC | Reduce 17.00% | −271,371 | −0.05 |
| ≡ | ACRSPUT – ACLARIS THERAPEUTICS INC | Buy | 500,000 | 0.05 |
| ≡ | SYRE – AEGLEA BIOTHERAPEUTICS INC | Buy | 81,116 | 0.03 |
| ≡ | VERU – VERU INC | Add 1113.00% | 1,000,000 | 0.02 |
| ≡ | MIRATI THERAPEUTICS INC | Sell | −200,000 | −0.02 |
| ≡ | VERONA PHARMA PLC | Sell | −500,000 | −0.02 |
| ≡ | VKTXCALL – VIKING THERAPEUTICS INC | Buy | 300,000 | 0.01 |
| ≡ | NBTX – NANOBIOTIX | Reduce 48.00% | −504,734 | 0.01 |
| ≡ | XBIPUT – SPDR SER TR | Sell | −150,000 | −0.00 |
| ≡ | APELLIS PHARMACEUTICALS INC | Buy | 100,000 | 0.00 |
| ≡ | CABA – CABALETTA BIO INC | Reduce 27.00% | −412,509 | −0.00 |
| ≡ | BTAIEURCALL – BIOXCEL THERAPEUTICS INC | Sell | −439,500 | −0.00 |
| ≡ |
| AMLX – AMYLYX PHARMACEUTICALS INC |
| Reduce 19.00% |
| −1,160,725 |
| −2.18 |
| ≡ | AKERO THERAPEUTICS INC | Add 271.00% | 1,417,150 | 2.03 |
| ≡ | VIR – VIR BIOTECHNOLOGY INC | Add 1277.00% | 1,816,070 | 1.29 |
| ≡ | BMRN – BIOMARIN PHARMACEUTICAL INC | Reduce 61.00% | −409,853 | −1.27 |
| ≡ | SNY – SANOFI | Sell | −768,101 | −1.23 |
| ≡ | MDT – MEDTRONIC PLC | Buy | 467,000 | 1.19 |
| ≡ | MEIRAGTX HLDGS PLC | Add 63.00% | 4,367,826 | 1.14 |
| ≡ | VERONA PHARMA PLC | Add 61.00% | 1,663,326 | 1.07 |
| ≡ | APELLIS PHARMACEUTICALS INC | Add 46.00% | 256,693 | 1.06 |
| ≡ | BELLUS HEALTH INC NEW | Sell | −4,952,538 | −1.05 |
| ≡ | PCVX – VAXCYTE INC | Add 38.00% | 444,122 | 1.04 |
| ≡ | MIRATI THERAPEUTICS INC | Reduce 54.00% | −855,031 | −0.98 |
| ≡ | LYRA – LYRA THERAPEUTICS INC | Add 39.00% | 3,610,832 | 0.97 |
| ≡ | IRON – DISC MEDICINE INC | Buy | 742,838 | 0.95 |
| ≡ | OBIO – ORCHESTRA BIOMED HLDGS INC | Reduce 10.00% | −225,358 | −0.90 |
| ≡ | HRMY – HARMONY BIOSCIENCES HLDGS IN | Add 791.00% | 791,370 | 0.81 |
| ≡ | IMVT – IMMUNOVANT INC | Add 95.00% | 1,231,925 | 0.79 |
| ≡ | SRPT – SAREPTA THERAPEUTICS INC | Reduce 69.00% | −179,784 | −0.79 |
| ≡ | ILMN – ILLUMINA INC | Buy | 145,000 | 0.79 |
| ≡ | ARGX – ARGENX SE | Buy | 69,000 | 0.78 |
| ≡ | CRNX – CRINETICS PHARMACEUTICALS IN | Reduce 45.00% | −1,607,950 | −0.67 |
| ≡ | NTRA – NATERA INC | Reduce 43.00% | −301,945 | −0.59 |
| ≡ | XENE – XENON PHARMACEUTICALS INC | Reduce 33.00% | −608,797 | −0.57 |
| ≡ | AXSM – AXSOME THERAPEUTICS INC | Buy | 271,493 | 0.56 |
| ≡ | PTGX – PROTAGONIST THERAPEUTICS INC | Add 52.00% | 504,609 | 0.52 |
| ≡ | TERNS PHARMACEUTICALS INC | Sell | −1,350,000 | −0.47 |
| ≡ | VBI VACCINES INC CDA | Sell | −52,335,002 | −0.47 |
| ≡ | INTRA-CELLULAR THERAPIES INC | Buy | 245,800 | 0.45 |
| ≡ | RAIN ONCOLOGY INC | Sell | −1,648,215 | −0.43 |
| ≡ | SPRINGWORKS THERAPEUTICS INC | Reduce 26.00% | −541,921 | −0.41 |
| ≡ | CABA – CABALETTA BIO INC | Add 113.00% | 820,223 | 0.40 |
| ≡ | ISRG – INTUITIVE SURGICAL INC | Sell | −50,000 | −0.38 |
| ≡ | CTKB – CYTEK BIOSCIENCES INC | Sell | −1,289,534 | −0.35 |
| ≡ | ROIV – ROIVANT SCIENCES LTD | Add 16.00% | 439,600 | 0.33 |
| ≡ | LRMR – LARIMAR THERAPEUTICS INC | Sell | −2,280,709 | −0.31 |
| ≡ | ZYME – ZYMEWORKS INC | Reduce 28.00% | −962,266 | −0.30 |
| ≡ | MORPHIC HLDG INC | Sell | −256,737 | −0.29 |
| ≡ | SOLENO THERAPEUTICS INC | Buy | 2,207,753 | 0.27 |
| ≡ | TERNS PHARMACEUTICALS INC | Buy | 1,075,000 | 0.27 |
| ≡ | RCKT – ROCKET PHARMACEUTICALS INC | Add 35.00% | 300,631 | 0.23 |
| ≡ | BHVN – BIOHAVEN LTD | Buy | 320,820 | 0.22 |
| ≡ | VKTX – VIKING THERAPEUTICS INC | Reduce 49.00% | −430,600 | −0.22 |
| ≡ | XBIPUT – SPDR SER TR | Add 50.00% | 50,000 | −0.22 |
| ≡ | BELLEROPHON THERAPEUTICS INC | Sell | −930,000 | −0.22 |
| ≡ | HILLEVAX INC | Sell | −406,024 | −0.20 |
| ≡ | COGT – COGENT BIOSCIENCES INC | Add 17.00% | 377,146 | 0.18 |
| ≡ | LANDOS BIOPHARMA INC | Buy | 1,486,991 | 0.18 |
| ≡ | TMCI – TREACE MED CONCEPTS INC | Reduce 9.00% | −225,000 | −0.17 |
| ≡ | IVERIC BIO INC | Reduce 66.00% | −332,000 | −0.17 |
| ≡ | AVADEL PHARMACEUTICALS PLC | Sell | −590,000 | −0.16 |
| ≡ | BMEA – BIOMEA FUSION INC | Add 120.00% | 391,441 | 0.16 |
| ≡ | VERU – VERU INC | Reduce 98.00% | −4,208,334 | −0.14 |
| ≡ | VBI VACCINES INC CDA | Buy | 1,381,355 | 0.13 |
| ≡ | LANDOS BIOPHARMA INC | Sell | −14,869,915 | −0.13 |
| ≡ | TCMD – TACTILE SYS TECHNOLOGY INC | Reduce 6.00% | −37,500 | 0.12 |
| ≡ | ACELYRIN INC | Buy | 200,000 | 0.12 |
| ≡ | IOVA – IOVANCE BIOTHERAPEUTICS INC | Reduce 8.00% | −1,303,325 | 0.09 |
| ≡ | ESTABLISHMENT LABS HLDGS INC | Reduce 9.00% | −42,933 | −0.09 |
| ≡ | ADC THERAPEUTICS SA | Sell | −1,495,805 | −0.09 |
| ≡ | PHENOMEX INC | Sell | −2,506,442 | −0.09 |
| ≡ | ASNSUSD – X4 PHARMACEUTICALS INC | Reduce 22.00% | −1,000,000 | 0.08 |
| ≡ | LEAP THERAPEUTICS INC | Sell | −6,726,496 | −0.07 |
| ≡ | BBIO – BRIDGEBIO PHARMA INC | Reduce 8.00% | −158,100 | −0.06 |
| ≡ | CAREMAX INC | Add 7.00% | 241,364 | 0.06 |
| ≡ | SINGULAR GENOMICS SYSTEMS IN | Reduce 28.00% | −919,061 | −0.06 |
| ≡ | TYRA – TYRA BIOSCIENCES INC | Reduce 27.00% | −134,403 | −0.06 |
| ≡ | CYPH – LEAP THERAPEUTICS INC | Buy | 586,733 | 0.05 |
| ≡ | AORT – ARTIVION INC | Reduce 14.00% | −154,508 | 0.04 |
| ≡ | ARQTPUT – ARCUTIS BIOTHERAPEUTICS INC | Buy | 300,000 | 0.04 |
| ≡ | DRIOEUR – DARIOHEALTH CORP | Sell | −313,869 | −0.04 |
| ≡ | CLOV – CLOVER HEALTH INVESTMENTS CO | Sell | −1,500,000 | −0.04 |
| ≡ | ATHENEX INC | Sell | −776,623 | −0.03 |
| ≡ | TARA – PROTARA THERAPEUTICS INC | Sell | −290,051 | −0.03 |
| ≡ | PROTHENA CORP PLC | Reduce 22.00% | −53,031 | 0.02 |
| ≡ | OUTSET MED INC | Reduce 17.00% | −187,067 | −0.02 |
| ≡ | MIRATI THERAPEUTICS INC | Buy | 200,000 | 0.02 |
| ≡ | POINT BIOPHARMA GLOBAL INC | Buy | 500,000 | 0.02 |
| ≡ | VERONA PHARMA PLC | Buy | 500,000 | 0.02 |
| ≡ | PEAR THERAPEUTICS INC | Sell | −900,548 | −0.01 |
| ≡ | BTAIEURCALL – BIOXCEL THERAPEUTICS INC | Buy | 439,500 | 0.00 |